Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children
Enterovirus 71 is a leading cause of hand-foot-and-mouth disease and herpangina. Here, the authors characterize a large panel of plasmablast-derived IgG mAbs that target the capsid of EV71 to identify neutralizing antibodies induced by natural infection.
Main Authors: | Kuan-Ying Arthur Huang, Mei-Feng Chen, Yhu-Chering Huang, Shin-Ru Shih, Cheng-Hsun Chiu, Jainn-Jim Lin, Jen-Ren Wang, Kuo-Chien Tsao, Tzou-Yien Lin |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-00736-9 |
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