Gene expression profiling and association with prion-related lesions in the medulla oblongata of symptomatic natural scrapie animals.

Gene expression profiling and association with prion-related lesions in the medulla oblongata of symptomatic natural scrapie animals.

The pathogenesis of natural scrapie and other prion diseases remains unclear. Examining transcriptome variations in infected versus control animals may highlight new genes potentially involved in some of the molecular mechanisms of prion-induced pathology. The aim of this work was to identify diseas...

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Bibliographic Details
Main Authors: Hicham Filali, Inmaculada Martin-Burriel, Frank Harders, Luis Varona, Jaber Lyahyai, Pilar Zaragoza, Martí Pumarola, Juan J Badiola, Alex Bossers, Rosa Bolea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3101219?pdf=render

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