Antidiabetics and antihypertensive medications use in Morocco: A pharmacoepidemiological descriptive study
Background: In Morocco, and many other African countries, there is a paucity of antihypertensive and antidiabetics use amongst the general population. Aim: To investigate the epidemiological profile of antihypertensive and antidiabetics use and analysis their adverse reactions. Setting: This study w...
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doaj-a29cac933eff467686c30402f8b3e3ad2020-11-25T03:16:41ZengAOSISAfrican Journal of Primary Health Care & Family Medicine2071-29282071-29362020-06-01121e1e610.4102/phcfm.v12i1.2195731Antidiabetics and antihypertensive medications use in Morocco: A pharmacoepidemiological descriptive studyElyamani Rida0Abdelmajid Soulaymani1Zineb Serhier2Hinde Hami3Mokhtari Abdelrhani4Laboratory of Genetics and Biometry, Department of Biology, Faculty of Sciences, Ibn Tofail University, KenitraLaboratory of Genetics and Biometry, Department of Biology, Faculty of Sciences, Ibn Tofail University, KenitraLaboratory of Medical Informatics, Department of Social Medicine and Community Health, Faculty of Medicine and Pharmacy, University of Hassan, CasablancaLaboratory of Genetics and Biometry, Department of Biology, Faculty of Sciences, Ibn Tofail University, KenitraLaboratory of Genetics and Biometry, Department of Biology, Faculty of Sciences, Ibn Tofail University, KenitraBackground: In Morocco, and many other African countries, there is a paucity of antihypertensive and antidiabetics use amongst the general population. Aim: To investigate the epidemiological profile of antihypertensive and antidiabetics use and analysis their adverse reactions. Setting: This study was conducted in the prefecture of Figuig, Morocco. Methods: A cross-sectional descriptive study. Data was collected using semi-structured questionnaire about their pharmacological treatment and presented using descriptive statistical analysis. Results: Sample of 244 subjects, predominantly women 58.15% (p 0.03) composed of diabetic patients 56.96% (n = 139) and hypertensive patients 43.03% (n = 105). After adjustments, 60.24% of all patients were under monotherapy. The diabetics were being treated using the Biguanide class (26.92%), insulin (20.0%) and sulfonylureas (10.0%) while hypertensive patients were treated by Calcium Channel Blockers (27.36%), Angiotensin Converting Enzyme Inhibitors (21.05%), Angiotensin T-Blockers (16.84%), Diuretics (7.36%) and β-adrenergic receptors blockers (3.15%). In total, 23.00% of all subjects have experienced negative side-effects, mostly, reported (90.38%) to health professionals and 23.52% of them have interrupted temporarily or try to change their treatment. Gastro-intestinal problems were the most adverse reactions reported (11.11%) followed by headache, dizziness and tinnitus (6.66%) and asthenia, feeling sick and feeling of faintness (5.33%). Conclusion: Managing diabetes and hypertension entails a lot of public challenges and requires more focus and interest, especially amongst the illiterate population in remote areas. Some of the suggested ways to help face the problem include the introduction of new innovative measures, systems of fellow-up and adverse reactions.https://phcfm.org/index.php/phcfm/article/view/2195pharmacoepidemiologyantidiabeticsantihypertensivemoroccopharmacovigilancemedication safety |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Elyamani Rida Abdelmajid Soulaymani Zineb Serhier Hinde Hami Mokhtari Abdelrhani |
spellingShingle |
Elyamani Rida Abdelmajid Soulaymani Zineb Serhier Hinde Hami Mokhtari Abdelrhani Antidiabetics and antihypertensive medications use in Morocco: A pharmacoepidemiological descriptive study African Journal of Primary Health Care & Family Medicine pharmacoepidemiology antidiabetics antihypertensive morocco pharmacovigilance medication safety |
author_facet |
Elyamani Rida Abdelmajid Soulaymani Zineb Serhier Hinde Hami Mokhtari Abdelrhani |
author_sort |
Elyamani Rida |
title |
Antidiabetics and antihypertensive medications use in Morocco: A pharmacoepidemiological descriptive study |
title_short |
Antidiabetics and antihypertensive medications use in Morocco: A pharmacoepidemiological descriptive study |
title_full |
Antidiabetics and antihypertensive medications use in Morocco: A pharmacoepidemiological descriptive study |
title_fullStr |
Antidiabetics and antihypertensive medications use in Morocco: A pharmacoepidemiological descriptive study |
title_full_unstemmed |
Antidiabetics and antihypertensive medications use in Morocco: A pharmacoepidemiological descriptive study |
title_sort |
antidiabetics and antihypertensive medications use in morocco: a pharmacoepidemiological descriptive study |
publisher |
AOSIS |
series |
African Journal of Primary Health Care & Family Medicine |
issn |
2071-2928 2071-2936 |
publishDate |
2020-06-01 |
description |
Background: In Morocco, and many other African countries, there is a paucity of antihypertensive and antidiabetics use amongst the general population.
Aim: To investigate the epidemiological profile of antihypertensive and antidiabetics use and analysis their adverse reactions.
Setting: This study was conducted in the prefecture of Figuig, Morocco.
Methods: A cross-sectional descriptive study. Data was collected using semi-structured questionnaire about their pharmacological treatment and presented using descriptive statistical analysis.
Results: Sample of 244 subjects, predominantly women 58.15% (p 0.03) composed of diabetic patients 56.96% (n = 139) and hypertensive patients 43.03% (n = 105). After adjustments, 60.24% of all patients were under monotherapy. The diabetics were being treated using the Biguanide class (26.92%), insulin (20.0%) and sulfonylureas (10.0%) while hypertensive patients were treated by Calcium Channel Blockers (27.36%), Angiotensin Converting Enzyme Inhibitors (21.05%), Angiotensin T-Blockers (16.84%), Diuretics (7.36%) and β-adrenergic receptors blockers (3.15%). In total, 23.00% of all subjects have experienced negative side-effects, mostly, reported (90.38%) to health professionals and 23.52% of them have interrupted temporarily or try to change their treatment. Gastro-intestinal problems were the most adverse reactions reported (11.11%) followed by headache, dizziness and tinnitus (6.66%) and asthenia, feeling sick and feeling of faintness (5.33%).
Conclusion: Managing diabetes and hypertension entails a lot of public challenges and requires more focus and interest, especially amongst the illiterate population in remote areas. Some of the suggested ways to help face the problem include the introduction of new innovative measures, systems of fellow-up and adverse reactions. |
topic |
pharmacoepidemiology antidiabetics antihypertensive morocco pharmacovigilance medication safety |
url |
https://phcfm.org/index.php/phcfm/article/view/2195 |
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