Unexplained Dyspnea in a Young Adult with Epstein–Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia?
Clinically, in young immunocompetent adults, Epstein-Barr virus (EBV) usually manifests as infectious mononucleosis (IM). Typical clinical findings of EBV IM include fever, profound fatigue, pharyngitis, bilateral posterior cervical adenopathy, and splenomegaly. Respiratory involvement with EBV IM m...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-09-01
|
Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/6/9/83 |
id |
doaj-a2b6eb5f016c482da57ddc2a984ec646 |
---|---|
record_format |
Article |
spelling |
doaj-a2b6eb5f016c482da57ddc2a984ec6462020-11-25T00:47:14ZengMDPI AGJournal of Clinical Medicine2077-03832017-09-01698310.3390/jcm6090083jcm6090083Unexplained Dyspnea in a Young Adult with Epstein–Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia?Burke A. Cunha0Scarlet Herrarte Fornos1Infectious Disease Division, Winthrop-University Hospital Mineola, NY 11501, USAInfectious Disease Division, Winthrop-University Hospital Mineola, NY 11501, USAClinically, in young immunocompetent adults, Epstein-Barr virus (EBV) usually manifests as infectious mononucleosis (IM). Typical clinical findings of EBV IM include fever, profound fatigue, pharyngitis, bilateral posterior cervical adenopathy, and splenomegaly. Respiratory involvement with EBV IM may occur, but is distinctly rare. We present a case of a 20 year old female who with classic EBV IM, but was inexplicably dyspneic and hypoxemic. Further diagnostic testing confirmed co-infection with Mycoplasma pneumoniae. As a non-zoonotic atypical community-acquired pneumonia (CAP), M. pneumoniae may rarely be accompanied by severe hypoxemia and even acute respiratory distress syndrome. She represented a diagnostic dilemma regarding the cause of her hypoxemia, i.e., due to EBV IM with pulmonary involvement or severe M. pneumoniae CAP. The patient slowly recovered with respiratory quinolone therapy.https://www.mdpi.com/2077-0383/6/9/83bacterial and viral co-infectionnon-exudative pharyngitiscommunity-acquired pneumoniaatypical pneumoniacold agglutininsatypical lymphocytosiselevated serum transaminases |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Burke A. Cunha Scarlet Herrarte Fornos |
spellingShingle |
Burke A. Cunha Scarlet Herrarte Fornos Unexplained Dyspnea in a Young Adult with Epstein–Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia? Journal of Clinical Medicine bacterial and viral co-infection non-exudative pharyngitis community-acquired pneumonia atypical pneumonia cold agglutinins atypical lymphocytosis elevated serum transaminases |
author_facet |
Burke A. Cunha Scarlet Herrarte Fornos |
author_sort |
Burke A. Cunha |
title |
Unexplained Dyspnea in a Young Adult with Epstein–Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia? |
title_short |
Unexplained Dyspnea in a Young Adult with Epstein–Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia? |
title_full |
Unexplained Dyspnea in a Young Adult with Epstein–Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia? |
title_fullStr |
Unexplained Dyspnea in a Young Adult with Epstein–Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia? |
title_full_unstemmed |
Unexplained Dyspnea in a Young Adult with Epstein–Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia? |
title_sort |
unexplained dyspnea in a young adult with epstein–barr virus infectious mononucleosis: pulmonary involvement or co-infection with mycoplasma pneumoniae pneumonia? |
publisher |
MDPI AG |
series |
Journal of Clinical Medicine |
issn |
2077-0383 |
publishDate |
2017-09-01 |
description |
Clinically, in young immunocompetent adults, Epstein-Barr virus (EBV) usually manifests as infectious mononucleosis (IM). Typical clinical findings of EBV IM include fever, profound fatigue, pharyngitis, bilateral posterior cervical adenopathy, and splenomegaly. Respiratory involvement with EBV IM may occur, but is distinctly rare. We present a case of a 20 year old female who with classic EBV IM, but was inexplicably dyspneic and hypoxemic. Further diagnostic testing confirmed co-infection with Mycoplasma pneumoniae. As a non-zoonotic atypical community-acquired pneumonia (CAP), M. pneumoniae may rarely be accompanied by severe hypoxemia and even acute respiratory distress syndrome. She represented a diagnostic dilemma regarding the cause of her hypoxemia, i.e., due to EBV IM with pulmonary involvement or severe M. pneumoniae CAP. The patient slowly recovered with respiratory quinolone therapy. |
topic |
bacterial and viral co-infection non-exudative pharyngitis community-acquired pneumonia atypical pneumonia cold agglutinins atypical lymphocytosis elevated serum transaminases |
url |
https://www.mdpi.com/2077-0383/6/9/83 |
work_keys_str_mv |
AT burkeacunha unexplaineddyspneainayoungadultwithepsteinbarrvirusinfectiousmononucleosispulmonaryinvolvementorcoinfectionwithmycoplasmapneumoniaepneumonia AT scarletherrartefornos unexplaineddyspneainayoungadultwithepsteinbarrvirusinfectiousmononucleosispulmonaryinvolvementorcoinfectionwithmycoplasmapneumoniaepneumonia |
_version_ |
1725261133664747520 |