On the Role of Store-Operated Calcium Entry in Acute and Chronic Neurodegenerative Diseases

On the Role of Store-Operated Calcium Entry in Acute and Chronic Neurodegenerative Diseases

In both excitable and non-excitable cells, calcium (Ca2+) signals are maintained by a highly integrated process involving store-operated Ca2+ entry (SOCE), namely the opening of plasma membrane (PM) Ca2+ channels following the release of Ca2+ from intracellular stores. Upon depletion of Ca2+ store,...

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Bibliographic Details
Main Authors: Agnese Secondo, Giacinto Bagetta, Diana Amantea
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Alzheimer’s disease
endoplasmic reticulum
Orai
Parkinson’s disease
SOCE
STIM
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2018.00087/full

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