Effect of hypertonic saline on mucociliary clearance and clinical outcomes in chronic bronchitis

Effect of hypertonic saline on mucociliary clearance and clinical outcomes in chronic bronchitis

Background Mucus dehydration and impaired mucus clearance are common features of cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). In CF, inhaled hypertonic saline (HS) improves lung function and produces sustained increases in mucociliary clearance (MCC). We hypothesised that a...

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Bibliographic Details
Main Authors: William D. Bennett, Ashley G. Henderson, Agathe Ceppe, Kirby L. Zeman, Jihong Wu, Christine Gladman, Fred Fuller, Stephen Gazda, Brian Button, Richard C. Boucher, Scott H. Donaldson
Format: Article
Language:English
Published: European Respiratory Society 2020-08-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/6/3/00269-2020.full

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