Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic review

Background and aims: The term “Food Allergy” refers to a complex global health problem with a wide spectrum of severity. However, a uniform definition of severe food allergy is currently missing. This systematic review is the preliminary step towards a state-of-the-art synopsis of the current eviden...

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Main Authors: Stefania Arasi, Ulugbek Nurmatov, Paul J. Turner, Ignacio J. Ansotegui, Shahd Daher, Audrey Dunn-Galvin, Motohiro Ebisawa, Philippe Eigenmann, Montserrat Fernandez-Rivas, Ruchi Gupta, Anna Nowak-Wegrzyn, Stavros Petrou, Graham Roberts, Mario A. Sánchez Borges, Sayantani B. Sindher, Luciana Kase Tanno, Marta Vazquez-Ortiz, Brian P. Vickery, Gary Wing-Kin Wong, Alessandro Fiocchi
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:World Allergy Organization Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455120303963
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author Stefania Arasi
Ulugbek Nurmatov
Paul J. Turner
Ignacio J. Ansotegui
Shahd Daher
Audrey Dunn-Galvin
Motohiro Ebisawa
Philippe Eigenmann
Montserrat Fernandez-Rivas
Ruchi Gupta
Anna Nowak-Wegrzyn
Stavros Petrou
Graham Roberts
Mario A. Sánchez Borges
Sayantani B. Sindher
Luciana Kase Tanno
Marta Vazquez-Ortiz
Brian P. Vickery
Gary Wing-Kin Wong
Alessandro Fiocchi
spellingShingle Stefania Arasi
Ulugbek Nurmatov
Paul J. Turner
Ignacio J. Ansotegui
Shahd Daher
Audrey Dunn-Galvin
Motohiro Ebisawa
Philippe Eigenmann
Montserrat Fernandez-Rivas
Ruchi Gupta
Anna Nowak-Wegrzyn
Stavros Petrou
Graham Roberts
Mario A. Sánchez Borges
Sayantani B. Sindher
Luciana Kase Tanno
Marta Vazquez-Ortiz
Brian P. Vickery
Gary Wing-Kin Wong
Alessandro Fiocchi
Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic review
World Allergy Organization Journal
Classification
Definition
Food allergy
Severity
author_facet Stefania Arasi
Ulugbek Nurmatov
Paul J. Turner
Ignacio J. Ansotegui
Shahd Daher
Audrey Dunn-Galvin
Motohiro Ebisawa
Philippe Eigenmann
Montserrat Fernandez-Rivas
Ruchi Gupta
Anna Nowak-Wegrzyn
Stavros Petrou
Graham Roberts
Mario A. Sánchez Borges
Sayantani B. Sindher
Luciana Kase Tanno
Marta Vazquez-Ortiz
Brian P. Vickery
Gary Wing-Kin Wong
Alessandro Fiocchi
author_sort Stefania Arasi
title Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic review
title_short Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic review
title_full Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic review
title_fullStr Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic review
title_full_unstemmed Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic review
title_sort consensus on definition of food allergy severity (defase): protocol for a systematic review
publisher Elsevier
series World Allergy Organization Journal
issn 1939-4551
publishDate 2020-12-01
description Background and aims: The term “Food Allergy” refers to a complex global health problem with a wide spectrum of severity. However, a uniform definition of severe food allergy is currently missing. This systematic review is the preliminary step towards a state-of-the-art synopsis of the current evidence relating to the severity of IgE-mediated food allergy; it will inform attempts to develop a consensus to define food allergy severity by clinicians and other stakeholders. Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published studies. Studies will be independently screened against pre-defined eligibility criteria and critically appraised by established instruments. Data will be descriptively and, if possible and applicable, quantitatively synthesised. Ethics and dissemination: This study does not require any specific ethical approval since it is a systematic review. We plan to report results from this systematic review in a peer reviewed journal. These results will be used to inform the development of an international consensus to define severe food allergy. Author's potential conflicts of interest are clearly stated. PROSPERO registration number: CRD42020183103.
topic Classification
Definition
Food allergy
Severity
url http://www.sciencedirect.com/science/article/pii/S1939455120303963
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spelling doaj-a2c802da200e4c0f951736e6bf73de652020-12-25T05:07:53ZengElsevierWorld Allergy Organization Journal1939-45512020-12-011312100493Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic reviewStefania Arasi0Ulugbek Nurmatov1Paul J. Turner2Ignacio J. Ansotegui3Shahd Daher4Audrey Dunn-Galvin5Motohiro Ebisawa6Philippe Eigenmann7Montserrat Fernandez-Rivas8Ruchi Gupta9Anna Nowak-Wegrzyn10Stavros Petrou11Graham Roberts12Mario A. Sánchez Borges13Sayantani B. Sindher14Luciana Kase Tanno15Marta Vazquez-Ortiz16Brian P. Vickery17Gary Wing-Kin Wong18Alessandro Fiocchi19Predictive and Preventive Medicine Research Unit, Multifactorial and Systemic Diseases Research Area, Pediatric Allergology Unit, Bambino Gesù Children’s Hospital IRCCS, Rome, Italy; Corresponding author. Pediatric Allergology Unit, Bambino Gesù Hospital (IRCCS), Piazza S. Onofrio, 00161, Rome, ItalyDivision of Population Medicine, School of Medicine, Cardiff University, Wales, UKNational Heart & Lung Institute, Imperial College London, London, UK; Discipline of Paediatrics and Child Health, School of Medicine, University of Sydney, Sydney, AustraliaDept. Allergy and Immunology, Hospital Quironsalud Bizkaia, Bilbao, SpainNuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, England, UKApplied Psychology and Paediatrics and Child Health, University College Cork, Cork, IrelandClinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, Kanagawa, JapanPediatric Allergy Unit, Department of Women-Children-Teenagers Pediatrics, University Hospitals of Geneva, Geneva, SwitzerlandServicio de Alergia, Hospital Clınico San Carlos, UCM, IdISSC, ARADyAL, Madrid, SpainCenter for Food Allergy and Asthma Research (CFAAR), Northwestern University Feinberg School of Medicine; Department of Pediatrics & Medicine, Ann & Robert H. Lurie Children’s Hospital of Chicago, USAAllergy and Immunology, Department of Pediatrics, New York University School of Medicine, Langone Health, New York, NY, USA; Department of Pediatrics, Gastroenterology and Nutrition, Collegium Medicum, University of Warmia and Mazury, Olsztyn, PolandNuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, England, UKNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Clinical and Experimental Sciences and Human Development in Health, Faculty of Medicine, University of Southampton, Southampton, UK; The David Hide Asthma and Allergy Research Centre, St Mary’s Hospital, Isle of Wight, UKAllergy and Clinical Immunology Department, Centro Médico Docente La Trinidad, Caracas, VenezuelaDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Stanford University, Stanford, CA, USA; Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford University, Stanford, CA, USAHospital Sírio Libanês, São Paulo, Brazil; University Hospital of Montpellier; Sorbonne Universités, Paris, Montpellier, FranceDepartment of Paediatrics, Imperial College, London, United KingdomDepartment of Pediatrics, Emory University, Atlanta, GA, USADepartment of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, ChinaPredictive and Preventive Medicine Research Unit, Multifactorial and Systemic Diseases Research Area, Pediatric Allergology Unit, Bambino Gesù Children’s Hospital IRCCS, Rome, ItalyBackground and aims: The term “Food Allergy” refers to a complex global health problem with a wide spectrum of severity. However, a uniform definition of severe food allergy is currently missing. This systematic review is the preliminary step towards a state-of-the-art synopsis of the current evidence relating to the severity of IgE-mediated food allergy; it will inform attempts to develop a consensus to define food allergy severity by clinicians and other stakeholders. Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published studies. Studies will be independently screened against pre-defined eligibility criteria and critically appraised by established instruments. Data will be descriptively and, if possible and applicable, quantitatively synthesised. Ethics and dissemination: This study does not require any specific ethical approval since it is a systematic review. We plan to report results from this systematic review in a peer reviewed journal. These results will be used to inform the development of an international consensus to define severe food allergy. Author's potential conflicts of interest are clearly stated. PROSPERO registration number: CRD42020183103.http://www.sciencedirect.com/science/article/pii/S1939455120303963ClassificationDefinitionFood allergySeverity