Social Freezing: Pressing Pause on Fertility

• Main Authors: Valentin Nicolae Varlas, Roxana Georgiana Bors, Dragos Albu, Ovidiu Nicolae Penes, Bogdana Adriana Nasui, Claudia Mehedintu, Anca Lucia Pop
• Format: Article
• Language: English
• Published: MDPI AG 2021-07-01
• Series: International Journal of Environmental Research and Public Health
• Subjects: social egg freezing; elective egg freezing; oocyte cryopreservation; fertility preservation; age-related infertility; oocyte vitrification
• Online Access: https://www.mdpi.com/1660-4601/18/15/8088
• ISSN: 1661-7827; 1660-4601

Increasing numbers of women are undergoing oocyte or tissue cryopreservation for medical or social reasons to increase their chances of having genetic children. Social egg freezing (SEF) allows women to preserve their fertility in anticipation of age-related fertility decline and ineffective fertility treatments at older ages. The purpose of this study was to summarize recent findings focusing on the challenges of elective egg freezing. We performed a systematic literature review on social egg freezing published during the last ten years. From the systematically screened literature, we identified and analyzed five main topics of interest during the last decade: (a) different fertility preservation techniques, (b) safety of freezing, (c) usage rate of frozen oocytes, (d) ethical considerations, and (e) cost-effectiveness of SEF. Fertility can be preserved for non-medical reasons through oocyte, embryos, or ovarian tissue cryopreservation, with oocyte vitrification being a new and optimal approach. Elective oocyte cryopreservation is better accepted, supports social gender equality, and enhances women’s reproductive autonomy. Despite controversies, planned oocyte cryopreservation appears as a chosen strategy against age-related infertility and may allow women to feel that they are more socially, psychologically, and financially stable before motherhood.