Accumulation of cholesterol, triglycerides and ceramides in hepatocellular carcinomas of diethylnitrosamine injected mice

Abstract Background Dysregulated lipid metabolism is critically involved in the development of hepatocellular carcinoma (HCC). The respective metabolic pathways affected in HCC can be identified using suitable experimental models. Mice injected with diethylnitrosamine (DEN) and fed a normal chow dev...

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Bibliographic Details
Main Authors: Elisabeth M. Haberl, Rebekka Pohl, Lisa Rein-Fischboeck, Marcus Höring, Sabrina Krautbauer, Gerhard Liebisch, Christa Buechler
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Lipids in Health and Disease
Subjects:
p53
Online Access:https://doi.org/10.1186/s12944-021-01567-w