Visualization of DC-SIGN-mediated entry pathway of engineered lentiviral vectors in target cells.
Dendritic cells (DCs) are potent antigen-presenting cells and therefore have enormous potential as vaccine targets. We have previously developed an engineered lentiviral vector (LV) that is pseudotyped with a mutated Sindbis virus glycoprotein (SVGmu), which is capable of targeting DCs through Dendr...
Main Authors: | Yarong Liu, April Tai, Kye-Il Joo, Pin Wang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3696072?pdf=render |
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