Basaloid follicular hamartoma: A case report and review of the literature

• Main Authors: Shu-Han Huang, Tien-Fa Hsiao, Chin-Cheng Lee
• Format: Article
• Language: English
• Published: Wiley 2012-01-01
• Series: Kaohsiung Journal of Medical Sciences
• Subjects: Basaloid follicular hamartoma; Infundibulocystic basal cell carcinoma; Skin adnexal tumor
• Online Access: http://www.sciencedirect.com/science/article/pii/S1607551X11001550

Basaloid follicular hamartoma (BFH) is a rare, benign, skin adnexal tumor. Several clinical patterns have been reported, but they all share the same histopathological features. BFH may be hereditary or nonhereditary and can be accompanied by systemic diseases. Microscopic examination of BFH shows branching cords and anastomosing strands of basaloid cells in a loose, fibrous stroma. The most important pathological differential diagnosis is infundibulocystic basal cell carcinoma. These two lesions must be differentiated carefully based on clinical presentation and histopathological picture, and even molecular studies may be needed. We present a report of a 78-year-old woman with a solitary, asymptomatic, slow-growing skin tumor on her left scalp. No associated systemic disorders were found. On the basis of an excisional biopsy performed on the tumor, a pathological diagnosis of sporadic BFH was made.