Gender difference in long- and short-term outcomes of off-pump coronary endarterectomy

• Main Authors: Feridoun Sabzi, Atefeh Asadmobini
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2020-01-01
• Series: Annals of Cardiac Anaesthesia
• Subjects: coronary endarterectomy; females; gender difference; males; off-pump coronary artery bypass graft
• Online Access: http://www.annals.in/article.asp?issn=0971-9784;year=2020;volume=23;issue=4;spage=419;epage=424;aulast=Sabzi

Background: The role of gender in the selection of the most effective method for treatment of patients with diffused coronary artery diseases remains a matter of debate. This study thus evaluated the effect of gender on long- and short-term outcomes of off-pump coronary endarterectomy (CE). Methods: This was a single-center retrospective study of patients who had undergone coronary artery bypass graft (CABG). The patients were divided into two groups, the CABG and the CABG + CE group, and further stratified into male and female. Long-term survival for each group was estimated by Kaplan–Meier analysis with log-rank testing. In addition, Cox regression analyses of each gender were also carried out to identify the predictors of the primary and secondary endpoints. Results: Overall, 25.8% of the patients were female. Diseased vessels were not statistically different in the two groups – men and women. There was no significant difference in postoperative outcomes between males and females in the CABG and CABG + CE groups. There was no significant difference in hospital mortality in the two groups between males and females. Kaplan–Meier curves show that there was no significant difference in the 5-year cardiac mortality between males and females belonging to the CABG and CABG + CE groups. Conclusion: The results of this study show that there was no significant difference in the short- and long-term outcomes of off-pump CABG and CE in both genders although women tend to carry a greater risk.