Connexin26-mediated transfer of laterality cues in Xenopus
Summary A cilia-driven leftward flow of extracellular fluid breaks bilateral symmetry in the dorsal midline of the neurula stage vertebrate embryo. The left-specific Nodal signaling cascade in the lateral plate mesoderm (LPM) is key to asymmetric morphogenesis and placement of organs during subseque...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2012-03-01
|
Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/1/5/473 |