In Astrocytes the Accumulation of the Immunity-Related GTPases Irga6 and Irgb6 at the Vacuole of Toxoplasma gondii Is Dependent on the Parasite Virulence

In Astrocytes the Accumulation of the Immunity-Related GTPases Irga6 and Irgb6 at the Vacuole of Toxoplasma gondii Is Dependent on the Parasite Virulence

Toxoplasma gondii is an obligate intracellular protozoan parasite responsible for a common infection of the central nervous system. Interferon (IFN)γ is the key cytokine of host defence against T. gondii. However, T. gondii strains d...

Full description

Bibliographic Details
Main Authors:	Felix P. Lubitz, Daniel Degrandi, Klaus Pfeffer, Anne K. Mausberg
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1155/2013/480231

Similar Items

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against <it>Toxoplasma gondii</it>
by: Uthaiah Revathy C, et al.
Published: (2011-01-01)

The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.
by: Oliver Liesenfeld, et al.
Published: (2011-01-01)

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.
by: Sascha Martens, et al.
Published: (2005-11-01)

Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPases.
Published: (2005-11-01)

Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death.
by: Yang O Zhao, et al.
Published: (2009-02-01)

Acidification of the parasitophorous vacuole containing Toxoplasma gondii in the presence of hydroxyurea
by: Cristiane S. Carvalho, et al.
Published: (2006-09-01)

A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse liver.
by: Jia Zeng, et al.
Published: (2009-08-01)

Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it.
by: Sebastian Virreira Winter, et al.
Published: (2011-01-01)

Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It
by: Caradonna, Kacey, et al.
Published: (2012)

Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii.
by: Tobias Steinfeldt, et al.
Published: (2010-12-01)

Correction: Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii.
by: Tobias Steinfeldt, et al.
Published: (2015-07-01)

Toxoplasma gondii, “new” genotypes and virulence
by: Dardé M.L.
Published: (2008-09-01)

Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection
by: Nora Steffens, et al.
Published: (2020-01-01)

Role of Toxoplasma gondii Chloroquine Resistance Transporter in Bradyzoite Viability and Digestive Vacuole Maintenance
by: Geetha Kannan, et al.
Published: (2019-08-01)

Contribution of the Residual Body in the Spatial Organization of Toxoplasma gondii Tachyzoites within the Parasitophorous Vacuole
by: S. Muñiz-Hernández, et al.
Published: (2011-01-01)

TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles
by: Clémence Foltz, et al.
Published: (2017-07-01)

Molecular basis of IRGB10 oligomerization and membrane association for pathogen membrane disruption
by: Hyun Ji Ha, et al.
Published: (2021-01-01)

A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles
by: Javier Periz, et al.
Published: (2019-09-01)

Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Regulate Maturation of the Cyst Wall
by: Rebekah B. Guevara, et al.
Published: (2020-01-01)

An overexpression screen of Toxoplasma gondii Rab-GTPases reveals distinct transport routes to the micronemes.
by: Katrin Kremer, et al.
Published: (2013-03-01)

Toxoplasma gondii and the Immunity-Related GTPase (IRG) resistance system in mice: a review
by: Yang Oliver Zhao, et al.
Published: (2009-03-01)

IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy.
by: Munir A Al-Zeer, et al.
Published: (2009-01-01)

Comparative virulence of Caribbean, Brazilian and European isolates of Toxoplasma gondii
by: Clare M. Hamilton, et al.
Published: (2019-03-01)

Cyst formation and reactivation of the virulent RH strain of Toxoplasma gondii
by: JAN, CHENG-JOU, et al.
Published: (1997)

Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes
by: Elisabeth Kravets, et al.
Published: (2016-01-01)

Toxoplasma gondii PPM3C, a secreted protein phosphatase, affects parasitophorous vacuole effector export.
by: Joshua Mayoral, et al.
Published: (2020-12-01)

Identification of a novel protein complex essential for effector translocation across the parasitophorous vacuole membrane of Toxoplasma gondii.
by: Nicole D Marino, et al.
Published: (2018-01-01)

In vitro multiplication of Toxoplasma gondii and Trypanosoma cruzi in mouse, rat, and hamster astrocytes
by: Adriana Troyo, et al.
Published: (2003-09-01)

Structural basis of surface antigen glycoprotein mediated virulence in Toxoplasma gondii
by: Bruic, Ekaterina
Published: (2009)

Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.
by: Elizabeth M Selleck, et al.
Published: (2013-01-01)

Structural Insights into the Architecture and Assembly of Microneme Protein 6 from Toxoplasma gondii
by: Sawmynaden, Kovilen
Published: (2009)

Requirement of Toxoplasma gondii metacaspases for IMC1 maturation, endodyogeny and virulence in mice
by: Muzi Li, et al.
Published: (2021-08-01)

Molecular mechanism for the control of virulent Toxoplasma gondii infections in wild-derived mice
by: Mateo Murillo-León, et al.
Published: (2019-03-01)

Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse
by: Jingtao Lilue, et al.
Published: (2013-10-01)

Lactate dehydrogenase in Toxoplasma gondii controls virulence, bradyzoite differentiation, and chronic infection.
by: Abdelbaset E Abdelbaset, et al.
Published: (2017-01-01)

Genotypes and mouse virulence of Toxoplasma gondii isolates from animals and humans in China.
by: Lin Wang, et al.
Published: (2013-01-01)

Protection induced by virus-like particles containing Toxoplasma gondii microneme protein 8 against highly virulent RH strain of Toxoplasma gondii infection.
by: Su-Hwa Lee, et al.
Published: (2017-01-01)

The Neurotropic Parasite Toxoplasma gondii Induces Astrocyte Polarization Through NFκB Pathway
by: Yu Jin, et al.
Published: (2019-11-01)

Dimensioning IRGA gas sampling systems: laboratory and field experiments
by: M. Aubinet, et al.
Published: (2016-03-01)

Toxoplasma gondii : étude du réseau de nanotubes membranaires de la vacuole parasitophore et des protéines GRA associées
by: Bittame, Amina
Published: (2011)