A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T
Abstracts: Functional magnetic resonance imaging (fMRI) in monkeys is important for bridging the gap between invasive animal brain studies and non-invasive human brain studies. To resolve the finer functional structure of the monkey brain, ultra-high-field (UHF) MR is essential, and high-performance...
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Elsevier
2020-02-01
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Series: | NeuroImage |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811919309875 |
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doaj-a349eb9f98104c5ea80590c19cd84c95 |
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record_format |
Article |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yang Gao Azma Mareyam Yi Sun Thomas Witzel Nicolas Arango Irene Kuang Jacob White Anna Wang Roe Lawrence Wald Jason Stockmann Xiaotong Zhang |
spellingShingle |
Yang Gao Azma Mareyam Yi Sun Thomas Witzel Nicolas Arango Irene Kuang Jacob White Anna Wang Roe Lawrence Wald Jason Stockmann Xiaotong Zhang A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T NeuroImage Magnetic resonance imaging (MRI) RF coil B0 shim Multi-coil shim Anesthetized monkey Multi-modal neuroimaging |
author_facet |
Yang Gao Azma Mareyam Yi Sun Thomas Witzel Nicolas Arango Irene Kuang Jacob White Anna Wang Roe Lawrence Wald Jason Stockmann Xiaotong Zhang |
author_sort |
Yang Gao |
title |
A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
title_short |
A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
title_full |
A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
title_fullStr |
A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
title_full_unstemmed |
A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
title_sort |
16-channel ac/dc array coil for anesthetized monkey whole-brain imaging at 7t |
publisher |
Elsevier |
series |
NeuroImage |
issn |
1095-9572 |
publishDate |
2020-02-01 |
description |
Abstracts: Functional magnetic resonance imaging (fMRI) in monkeys is important for bridging the gap between invasive animal brain studies and non-invasive human brain studies. To resolve the finer functional structure of the monkey brain, ultra-high-field (UHF) MR is essential, and high-performance, close-fitting RF receive coils are typically desired to fully leverage the intrinsic gains provided by UHF MRI. Moreover, static field (B0) inhomogeneity arising from the tissue susceptibility interface is more severe at UHF, presenting an obstacle to achieving high-resolution fMRI. B0 shim of the monkey head is challenging due to its smaller size and more complex sources of B0 offsets in multi-modal imaging tasks. In the present work, we have customized an array coil for lightly-anesthetized monkey fMRI in the 7T human scanner that combines RF and multi-coil (MC) B0 shim functionality (also referred to as AC/DC coils) to provide high imaging SNR and high-spatial-order, rapidly switchable B0-shim capability. Additional space was retained on the coil to render it compatible with monkey multi-modal imaging studies. Both MC global (whole-volume) and dynamic (slice-optimized) shim methods were tested and evaluated, and the benefits of MC shim for fMRI experiments was also studied. A minor reduction in RF coil performance was found after introducing additional B0 shim circuitry. However, the proposed RF coil provided higher image SNR and more uniform contrast compared to a commercially available coil for human knee imaging. Compared with static 2nd-order shim, the B0 inhomogeneity was reduced by 56.8%, and 95-percentile B0 offset was reduced to within 28.2 Hz through MC shim, versus 68.7 Hz with 2nd-order static shim. As a result, functional image quality could be improved, and brain activation can be better detected using the proposed AC/DC monkey coil. |
topic |
Magnetic resonance imaging (MRI) RF coil B0 shim Multi-coil shim Anesthetized monkey Multi-modal neuroimaging |
url |
http://www.sciencedirect.com/science/article/pii/S1053811919309875 |
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doaj-a349eb9f98104c5ea80590c19cd84c952020-11-25T03:12:13ZengElsevierNeuroImage1095-95722020-02-01207116396A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7TYang Gao0Azma Mareyam1Yi Sun2Thomas Witzel3Nicolas Arango4Irene Kuang5Jacob White6Anna Wang Roe7Lawrence Wald8Jason Stockmann9Xiaotong Zhang10Interdisciplinary Institute of Neuroscience and Technology, Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States; School of Medicine, Zhejiang University, Hangzhou, ChinaAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United StatesMR Collaboration, Siemens Healthcare, Shanghai, ChinaAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United StatesDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United StatesDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United StatesDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United StatesInterdisciplinary Institute of Neuroscience and Technology, Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China; School of Medicine, Zhejiang University, Hangzhou, ChinaAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United StatesAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United States; Corresponding author. Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United StatesInterdisciplinary Institute of Neuroscience and Technology, Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China; School of Medicine, Zhejiang University, Hangzhou, China; Corresponding author. Interdisciplinary Institute of Neuroscience and Technology, Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, ChinaAbstracts: Functional magnetic resonance imaging (fMRI) in monkeys is important for bridging the gap between invasive animal brain studies and non-invasive human brain studies. To resolve the finer functional structure of the monkey brain, ultra-high-field (UHF) MR is essential, and high-performance, close-fitting RF receive coils are typically desired to fully leverage the intrinsic gains provided by UHF MRI. Moreover, static field (B0) inhomogeneity arising from the tissue susceptibility interface is more severe at UHF, presenting an obstacle to achieving high-resolution fMRI. B0 shim of the monkey head is challenging due to its smaller size and more complex sources of B0 offsets in multi-modal imaging tasks. In the present work, we have customized an array coil for lightly-anesthetized monkey fMRI in the 7T human scanner that combines RF and multi-coil (MC) B0 shim functionality (also referred to as AC/DC coils) to provide high imaging SNR and high-spatial-order, rapidly switchable B0-shim capability. Additional space was retained on the coil to render it compatible with monkey multi-modal imaging studies. Both MC global (whole-volume) and dynamic (slice-optimized) shim methods were tested and evaluated, and the benefits of MC shim for fMRI experiments was also studied. A minor reduction in RF coil performance was found after introducing additional B0 shim circuitry. However, the proposed RF coil provided higher image SNR and more uniform contrast compared to a commercially available coil for human knee imaging. Compared with static 2nd-order shim, the B0 inhomogeneity was reduced by 56.8%, and 95-percentile B0 offset was reduced to within 28.2 Hz through MC shim, versus 68.7 Hz with 2nd-order static shim. As a result, functional image quality could be improved, and brain activation can be better detected using the proposed AC/DC monkey coil.http://www.sciencedirect.com/science/article/pii/S1053811919309875Magnetic resonance imaging (MRI)RF coilB0 shimMulti-coil shimAnesthetized monkeyMulti-modal neuroimaging |