Highly pure and expandable PSA-NCAM-positive neural precursors from human ESC and iPSC-derived neural rosettes.

Highly pure and expandable PSA-NCAM-positive neural precursors from human ESC and iPSC-derived neural rosettes.

Homogeneous culture of neural precursor cells (NPCs) derived from human pluripotent stem cells (hPSCs) would provide a powerful tool for biomedical applications. However, previous efforts to expand mechanically dissected neural rosettes for cultivation of NPCs remain concerns regarding non-neural ce...

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Bibliographic Details
Main Authors: Dae-Sung Kim, Dongjin R Lee, Han-Soo Kim, Jeong-Eun Yoo, Sung Jun Jung, Bo Young Lim, Jiho Jang, Hoon-Chul Kang, Seungkwon You, Dong-Youn Hwang, Joong Woo Leem, Taick Sang Nam, Sung-Rae Cho, Dong-Wook Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3401209?pdf=render

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