Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium.

Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium.

Several deleterious intra-acinar phenomena are simultaneously triggered on initiating acute pancreatitis. These culminate in acinar injury or inflammatory mediator generation in vitro and parenchymal damage in vivo. Supraphysiologic caerulein is one such initiator which simultaneously activates nume...

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Bibliographic Details
Main Authors: Vivek Mishra, Rachel Cline, Pawan Noel, Jenny Karlsson, Catherine J Baty, Lidiya Orlichenko, Krutika Patel, Ram Narayan Trivedi, Sohail Z Husain, Chathur Acharya, Chandra Durgampudi, Donna B Stolz, Sarah Navina, Vijay P Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688910?pdf=render

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