Decorin-mediated suppression of tumorigenesis, invasion, and metastasis in inflammatory breast cancer
Xiaoding Hu et al. find that expression of the proteoglycan decorin is decreased in patients with inflammatory breast cancer compared to normal breast tissue and some other types of breast cancer. They demonstrate that decorin acts as a tumor suppressor in cancer cells and human xenograft mouse mode...
Main Authors: | Xiaoding Hu, Emilly S. Villodre, Richard Larson, Omar M. Rahal, Xiaoping Wang, Yun Gong, Juhee Song, Savitri Krishnamurthy, Naoto T. Ueno, Debu Tripathy, Wendy A. Woodward, Bisrat G. Debeb |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-020-01590-0 |
Similar Items
-
Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion
by: Emilly S. Villodre, et al.
Published: (2021-10-01) -
NDRG1 Expression Is an Independent Prognostic Factor in Inflammatory Breast Cancer
by: Emilly S. Villodre, et al.
Published: (2020-12-01) -
The Protective Role of Decorin in Hepatic Metastasis of Colorectal Carcinoma
by: Andrea Reszegi, et al.
Published: (2020-08-01) -
Non-glycanated Decorin Is a Drug Target on Human Adipose Stromal Cells
by: Alexes C. Daquinag, et al.
Published: (2017-09-01) -
Ablation of Stromal Cells with a Targeted Proapoptotic Peptide Suppresses Cancer Chemotherapy Resistance and Metastasis
by: Fei Su, et al.
Published: (2020-09-01)