Expression of P. falciparum var genes involves exchange of the histone variant H2A.Z at the promoter.
Plasmodium falciparum employs antigenic variation to evade the human immune response by switching the expression of different variant surface antigens encoded by the var gene family. Epigenetic mechanisms including histone modifications and sub-nuclear compartmentalization contribute to transcriptio...
Main Authors: | Michaela Petter, Chin Chin Lee, Timothy J Byrne, Katja E Boysen, Jennifer Volz, Stuart A Ralph, Alan F Cowman, Graham V Brown, Michael F Duffy |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-02-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3040674?pdf=render |
Similar Items
-
The histone variant H2A.Z in gene regulation
by: Benedetto Daniele Giaimo, et al.
Published: (2019-06-01) -
Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates
by: Helbing Caren C, et al.
Published: (2009-12-01) -
Preparing for Transcription: The Role of Histone H2A.Z.
Published: (2005-12-01) -
Regulation and function of histone variant H2A.Z during T-cell development
by: Hooper, Joel
Published: (2006) -
Genetic interactions between variant histone H2.A.Z and putative targets
by: Chen, Jin Song
Published: (2005)