BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication

BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication

Summary: BET bromodomain proteins are required for oncogenic transcription activities, and BET inhibitors have been rapidly advanced into clinical trials. Understanding the effects of BET inhibition on processes such as DNA replication will be important for future clinical applications. Here, we sho...

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Bibliographic Details
Main Authors:	Akhil Bowry, Ann Liza Piberger, Patricia Rojas, Marco Saponaro, Eva Petermann
Format:	Article
Language:	English
Published:	Elsevier 2018-11-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124718316838

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