BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
Summary: BET bromodomain proteins are required for oncogenic transcription activities, and BET inhibitors have been rapidly advanced into clinical trials. Understanding the effects of BET inhibition on processes such as DNA replication will be important for future clinical applications. Here, we sho...
Main Authors: | Akhil Bowry, Ann Liza Piberger, Patricia Rojas, Marco Saponaro, Eva Petermann |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-11-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718316838 |
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