Nitrosative stress induces DNA strand breaks but not caspase mediated apoptosis in a lung cancer cell line

Nitrosative stress induces DNA strand breaks but not caspase mediated apoptosis in a lung cancer cell line

<p>Abstract</p> <p>Background</p> <p>Key steps crucial to the process of tumor progression are genomic instability and escape from apoptosis. Nitric oxide and its interrelated reactive intermediates (collectively denoted as NO<sub>X</sub>) have been implicat...

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Bibliographic Details
Main Authors: Bentz Brandon G, Hammer Neal D, Radosevich James A, Haines G Kenneth
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2004-12-01
Series:Journal of Carcinogenesis
Subjects:
Nitric Oxide
DNA Strand Breaks
Online Access:http://www.carcinogenesis.com/content/3/1/16

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