Role of Preoperative Chemoradiotherapy in Clinical Stage II/III Rectal Cancer Patients Undergoing Total Mesorectal Excision: A Retrospective Propensity Score Analysis

Role of Preoperative Chemoradiotherapy in Clinical Stage II/III Rectal Cancer Patients Undergoing Total Mesorectal Excision: A Retrospective Propensity Score Analysis

BackgroundAlthough the current standard preoperative chemoradiotherapy (PCRT) for stage II/III rectal cancer decreases the risk of local recurrence, it does not improve survival and increases the likelihood of preoperative overtreatment, especially in patients without circumferential resection margi...

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Main Authors: Jii Bum Lee, Han Sang Kim, Ahrong Ham, Jee Suk Chang, Sang Jun Shin, Seung-Hoon Beom, Woong Sub Koom, Taeil Kim, Yoon Dae Han, Dai Hoon Han, Hyuk Hur, Byung Soh Min, Kang Young Lee, Nam Kyu Kim, Yu Rang Park, Joon Seok Lim, Joong Bae Ahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
stage II/III
rectal cancer
total mesorectal excision
upfront surgery
chemoradiotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.609313/full

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