The monoclonal S9.6 antibody exhibits highly variable binding affinities towards different R-loop sequences.

The monoclonal S9.6 antibody exhibits highly variable binding affinities towards different R-loop sequences.

The monoclonal antibody S9.6 is a widely-used tool to purify, analyse and quantify R-loop structures in cells. A previous study using the surface plasmon resonance technology and a single-chain variable fragment (scFv) of S9.6 showed high affinity (0.6 nM) for DNA-RNA and also a high affinity (2.7 n...

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Bibliographic Details
Main Authors:	Fabian König, Thomas Schubert, Gernot Längst
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2017-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC5464589?pdf=render

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