Combination of ELISA screening and seroneutralisation tests to expedite Zika virus seroprevalence studies

Combination of ELISA screening and seroneutralisation tests to expedite Zika virus seroprevalence studies

Abstract Here we propose a strategy allowing implementing efficient and practicable large-scale seroepidemiological studies for Zika Virus (ZIKV). It combines screening by a commercial NS1 protein-based Zika IgG ELISA, and confirmation by a cytopathic effect-based virus neutralization test (CPE-base...

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Bibliographic Details
Main Authors: Elif Nurtop, Paola Mariela Saba Villarroel, Boris Pastorino, Laetitia Ninove, Jan Felix Drexler, Yelin Roca, Bouba Gake, Audrey Dubot-Peres, Gilda Grard, Christophe Peyrefitte, Stéphane Priet, Xavier de Lamballerie, Pierre Gallian
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Virology Journal
Subjects:
Zika virus
Seroepidemiology
Virus neutralization test
Online Access:http://link.springer.com/article/10.1186/s12985-018-1105-5

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