Beclin-1–Dependent Autophagy Improves Outcomes of Pneumonia-Induced Sepsis

Beclin-1–Dependent Autophagy Improves Outcomes of Pneumonia-Induced Sepsis

ObjectiveWe previously demonstrated that promoting Beclin-1–dependent autophagy is cardiac protective during endotoxemia shock, suggesting that autophagy-based approaches may become a promising therapeutic strategy for sepsis. In this study, we applied both genetic and pharmacological approaches to...

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Bibliographic Details
Main Authors: Azadeh Nikouee, Matthew Kim, Xiangzhong Ding, Yuxiao Sun, Qun S. Zang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
autophagy
pneumonia
sepsis
infection
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.706637/full

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