CO2 measurement for the early differential diagnosis of pulmonary embolism-related shock at the emergency department: A case series

Objective: An early differential diagnosis is mandatory when facing a patient with clinical shock of unclear aetiology, in order to guide proper treatment. We assessed if the expired CO2 measurement and alveolar-arterial CO2 calculation could improve the differential diagnosis of shock during its in...

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Bibliographic Details
Main Authors: Cédric Van Marcke, Anas Daoudia, Andrea Penaloza, Franck Verschuren
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Respiratory Medicine Case Reports
Subjects:
CO2
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007115300356
Description
Summary:Objective: An early differential diagnosis is mandatory when facing a patient with clinical shock of unclear aetiology, in order to guide proper treatment. We assessed if the expired CO2 measurement and alveolar-arterial CO2 calculation could improve the differential diagnosis of shock during its initial presentation, particularly in separating pulmonary embolism from other causes of shock. Methods: We analysed the charts of 12 patients who presented with clinical shock and had end-tidal CO2 (EtCO2) and arterial CO2 partial pressure (PaCO2) measurements. Results: In cases with pulmonary embolism-related shock (n = 3), the gradient between PaCO2 and EtCO2 was increased (37 vs 0.2 mmHg). There was a similar trend for a higher PaCO2 value (60 vs 32.2 mmHg) and a lower EtCO2 value (23 vs 32 mmHg). Conclusion: An initial CO2 measurement might be an easily available tool for the early diagnostic work-up of clinical shock.
ISSN:2213-0071