APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression
Abstract Background Canonical WNT signalling plays a critical role in the regulation of ovarian development; mis-regulation of this key pathway in the adult ovary is associated with subfertility and tumourigenesis. The roles of Adenomatous polyposis coli 2 (APC2), a little-studied WNT signalling pat...
Main Authors: | Noha-Ehssan Mohamed, Trevor Hay, Karen R. Reed, Matthew J. Smalley, Alan R. Clarke |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12885-019-5867-y |
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