Evaluation of the Graves’ Orbitopathy-Specific Quality of Life Questionnaire in the Mainland Chinese Population
Purpose. To study the clinical significance of the Graves’ orbitopathy-specific quality of life (GO-QOL) questionnaire in mainland Chinese patients. Methods. A cross-sectional study was performed at the Ophthalmology Department of the Sun Yat-sen Memorial Hospital from April 2017 to April 2018. Eigh...
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doaj-a3fd0af775074be9a2df42828a931d712020-11-25T03:36:05ZengHindawi LimitedJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/76024197602419Evaluation of the Graves’ Orbitopathy-Specific Quality of Life Questionnaire in the Mainland Chinese PopulationPeng Zeng0Shu-xian Fan1Zi-jing Li2Yuan-yu Peng3Yu-xin Hu4Ming-tong Xu5Mei Wang6Department of Ophthalmology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, ChinaDepartment of Ophthalmology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, ChinaDepartment of Ophthalmology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, ChinaDepartment of Ophthalmology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, ChinaDepartment of Ophthalmology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, ChinaDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, ChinaDepartment of Ophthalmology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, ChinaPurpose. To study the clinical significance of the Graves’ orbitopathy-specific quality of life (GO-QOL) questionnaire in mainland Chinese patients. Methods. A cross-sectional study was performed at the Ophthalmology Department of the Sun Yat-sen Memorial Hospital from April 2017 to April 2018. Eighty-eight consecutive Graves’ orbitopathy (GO) patients completed the two subscales of the GO-QOL questionnaire: visual functioning and appearance. The disease severity of GO was measured by the European Group on Graves’ Orbitopathy (EUGOGO) classification, and clinical activity was evaluated by the clinical activity score (CAS). Results. The mean scores of GO-QOL questionnaire for the visual functioning and appearance subscales were 68.4 ± 31.2 and 62.0 ± 27.4, respectively. Lower QOL scores for the visual functioning subscale were significantly correlated with disease severity, the CAS and diplopia (all p<0.05). Lower QOL scores for appearance were significantly correlated with the CAS (p<0.05). Although no correlation was found between the appearance subscale scores and disease severity (p=0.407), a downward trend in the appearance subscale scores as the severity of GO increased from mild to sight-threatening GO was found. Conclusion. A strong correlation between disease severity and clinical activity has been shown in the GO-QOL questionnaire, suggested by the EUGOGO. The GO-QOL questionnaire is a simple and effective appraisal instrument in the evaluation of health-related QOL in the mainland Chinese patients with GO.http://dx.doi.org/10.1155/2019/7602419 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Peng Zeng Shu-xian Fan Zi-jing Li Yuan-yu Peng Yu-xin Hu Ming-tong Xu Mei Wang |
spellingShingle |
Peng Zeng Shu-xian Fan Zi-jing Li Yuan-yu Peng Yu-xin Hu Ming-tong Xu Mei Wang Evaluation of the Graves’ Orbitopathy-Specific Quality of Life Questionnaire in the Mainland Chinese Population Journal of Ophthalmology |
author_facet |
Peng Zeng Shu-xian Fan Zi-jing Li Yuan-yu Peng Yu-xin Hu Ming-tong Xu Mei Wang |
author_sort |
Peng Zeng |
title |
Evaluation of the Graves’ Orbitopathy-Specific Quality of Life Questionnaire in the Mainland Chinese Population |
title_short |
Evaluation of the Graves’ Orbitopathy-Specific Quality of Life Questionnaire in the Mainland Chinese Population |
title_full |
Evaluation of the Graves’ Orbitopathy-Specific Quality of Life Questionnaire in the Mainland Chinese Population |
title_fullStr |
Evaluation of the Graves’ Orbitopathy-Specific Quality of Life Questionnaire in the Mainland Chinese Population |
title_full_unstemmed |
Evaluation of the Graves’ Orbitopathy-Specific Quality of Life Questionnaire in the Mainland Chinese Population |
title_sort |
evaluation of the graves’ orbitopathy-specific quality of life questionnaire in the mainland chinese population |
publisher |
Hindawi Limited |
series |
Journal of Ophthalmology |
issn |
2090-004X 2090-0058 |
publishDate |
2019-01-01 |
description |
Purpose. To study the clinical significance of the Graves’ orbitopathy-specific quality of life (GO-QOL) questionnaire in mainland Chinese patients. Methods. A cross-sectional study was performed at the Ophthalmology Department of the Sun Yat-sen Memorial Hospital from April 2017 to April 2018. Eighty-eight consecutive Graves’ orbitopathy (GO) patients completed the two subscales of the GO-QOL questionnaire: visual functioning and appearance. The disease severity of GO was measured by the European Group on Graves’ Orbitopathy (EUGOGO) classification, and clinical activity was evaluated by the clinical activity score (CAS). Results. The mean scores of GO-QOL questionnaire for the visual functioning and appearance subscales were 68.4 ± 31.2 and 62.0 ± 27.4, respectively. Lower QOL scores for the visual functioning subscale were significantly correlated with disease severity, the CAS and diplopia (all p<0.05). Lower QOL scores for appearance were significantly correlated with the CAS (p<0.05). Although no correlation was found between the appearance subscale scores and disease severity (p=0.407), a downward trend in the appearance subscale scores as the severity of GO increased from mild to sight-threatening GO was found. Conclusion. A strong correlation between disease severity and clinical activity has been shown in the GO-QOL questionnaire, suggested by the EUGOGO. The GO-QOL questionnaire is a simple and effective appraisal instrument in the evaluation of health-related QOL in the mainland Chinese patients with GO. |
url |
http://dx.doi.org/10.1155/2019/7602419 |
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