Summary: | The Tuul River Basin is the most important socioeconomic and political base area of Mongolia. Therefore, studying the interrelationships between changes in the ecohydrological processes of this basin and its land cover is of great importance for maintaining sustainability and the environment. This study investigated the annual average air temperature, total annual precipitation, and river discharge variability, and land cover changes at selected stations of the basin by using the hydrometeorological analysis, satellite analysis, and land cover determination statistical analysis. During the study period, the average annual air temperature rose from −1.5 °C to +0.3 °C (1.8 °C). The average annual precipitation exhibits relatively low change during this period. River discharge varied during the study period. A significant decreasing trend in river discharge was observed at the Terelj (<i>φ</i> = −2.72) and Ulaanbaatar (<i>φ</i> = −5.63) stations, whereas the other stations, Altanbulag, Lun, and Orkhontuul, showed a significant increasing trend. During the study period, changes in land cover were directly related to main hydrometeorological parameters. Between 2000 and 2020, the amount of grassland decreased by 319.67 km<sup>2</sup>, while the area of water bodies increased by 28.36 km<sup>2</sup>. In the study area, mainly water bodies and sensitive areas of the land cover types were changed due to changes in precipitation. Studies in the arid and semiarid regions of Central Asia show that changes of ecohydrological processes have a significant impact on land cover changes.
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