Atorvastatin and diacerein reduce insulin resistance and increase disease tolerance in rats with sepsis

Atorvastatin and diacerein reduce insulin resistance and increase disease tolerance in rats with sepsis

Abstract Background Sepsis is one of the leading causes of death among hospitalized patients. At the onset of this condition, there is an over-production of pro-inflammatory mediators that contribute to organ failure and death. The excess production of pro-inflammatory mediators also impairs insulin...

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Bibliographic Details
Main Authors: K. L. C. da Silva, A. P. Camacho, F. C. Mittestainer, B. M. Carvalho, A. Santos, D. Guadagnini, A. G. Oliveira, M. J. A. Saad
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Inflammation
Subjects:
Statin
Diacerein
Insulin resistance
Sepsis
Online Access:http://link.springer.com/article/10.1186/s12950-018-0184-9

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http://link.springer.com/article/10.1186/s12950-018-0184-9

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