Oxidation of 7-dehydrocholesterol by a mouse liver microsomal system dependent on reduced pyridine nucleotides

Oxidation of 7-dehydrocholesterol by a mouse liver microsomal system dependent on reduced pyridine nucleotides

Aerobic incubation of 7-dehydrocholesterol with mouse liver microsomes in the presence of a detergent, an iron salt, and NADH or NADPH resulted in the conversion of the sterol to more polar products. In the presence of Fe3+ or low levels of Fe2+ the reaction was dependent upon reduced pyridine nucle...

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Bibliographic Details
Main Author: A.A. Kandutsch
Format: Article
Language:English
Published: Elsevier 1966-09-01
Series:Journal of Lipid Research
Subjects:
7-dehydrocholesterol
enzymatic oxidation
pyridine nucleotide dependence
mouse liver
autoxidation
microsomal lipids
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520392403

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http://www.sciencedirect.com/science/article/pii/S0022227520392403

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