Transcriptome and N6-Methyladenosine RNA Methylome Analyses in Aortic Dissection and Normal Human Aorta

Transcriptome and N6-Methyladenosine RNA Methylome Analyses in Aortic Dissection and Normal Human Aorta

Objective: To investigate the N6-methyladenosine (m6A) modification and the expressions of the m6A regulatory genes in the acute aortic dissection (AD).Methods: MeRIP-seq and RNA-seq experiments of aortic media tissue samples obtained from AD (n = 4) and Controls (n = 4) were conducted. m6A methylat...

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Bibliographic Details
Main Authors: Xianwu Zhou, Zerui Chen, Jianrong Zhou, Yaorong Liu, Ruixin Fan, Tucheng Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
aortic dissection
transcriptome analysis
N6-methyladenosine RNA methylome analysis
extracellular matrix
inflammatory responses three
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.627380/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.627380/full

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