Clinical and epidemiological round: journal club

• Main Authors: Mendoza Mendoza, Deibie Yesith, Soto Tirado, Susana, Caraballo Cordovez, César
• Format: Article
• Language: Spanish
• Published: Universidad de Antioquia 2018-10-01
• Series: Iatreia
• Subjects: Breast Neoplasms; Chronic Kidney Disease; Contraception; Education; Fluid Therapy; Lactic Acidosis; Metformin; Myopia; Postoperative Complications; Risk Assessment; Survival Rate
• Online Access: http://aprendeenlinea.udea.edu.co/revistas/index.php/iatreia/article/view/334402/20791231

In this new edition of the Clinical and Epidemiologic Round, the reader will find four articles that we have considered of special relevance for current clinical practice. In a pragmatic, multicenter and randomized controlled trial, Myles et al compared a restrictive versus liberal intravenous-fluid strategy for patients undergoing major abdominal surgery evaluating disability-free survival after one year. Furthermore, Mørch et al, present a Danish prospective cohort evaluating the association between the use of oral contraceptives and risk of invasive breast cancer. Additionally, in a community-based cohort study, Lazarus et al aimed to quantify the association between metformin use and hospitalization with acidosis across the range of estimated glomerular filtration rate. At last, using a mendelian randomization study, Mountjoy et al aimed to determine whether more years spent in education is a causal risk factor for myopia or, conversely, whether myopia is a causal risk factor for more years in education.