Demographic and clinico-pathological profile of carcinoma stomach in a tertiary referral centre of Eastern India
Objectives: This prospective study was done to assess the incidence, clinical presentations, histopathological subtypes of gastric adenocarcinoma in a referral institute of Eastern India. Methods: The patients admitted with diagnosis of gastric carcinoma in a tertiary referral hospital in Eastern In...
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Al Ameen Medical College
2012-10-01
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doaj-a4475e23b5fc4bdeb286a4e8aed57a012020-11-25T02:02:57ZengAl Ameen Medical CollegeAl Ameen Journal of Medical Sciences0974-11432012-10-010504398402Demographic and clinico-pathological profile of carcinoma stomach in a tertiary referral centre of Eastern IndiaShyamal Kumar HalderProsanta Kumar BhattacharjeePartha BharPrasenjit BhattacharyaAnadi PachauryRanu Roy BiswasPranjal PandeyObjectives: This prospective study was done to assess the incidence, clinical presentations, histopathological subtypes of gastric adenocarcinoma in a referral institute of Eastern India. Methods: The patients admitted with diagnosis of gastric carcinoma in a tertiary referral hospital in Eastern India between January2006 to December2010 were included in this study. Data were compiled and analyzed with regards to their age, sex, socioeconomic status, their clinical presentations, site of lesion & histopathological subtypes. Results: 150 patients were included in this study of which 50 patients were of ≤50 years age. The median age group was 57 years. The male: female ratio was 2.3:1. Most of the patients were from lower socioeconomic strata (55.33%). Anemia (41.33%) and weight loss (38%) were the predominant presenting features irrespective of age, whereas gastric outlet obstruction due to antral growths was the commonest presentation in patients of ≤50 years age group. The most common histopathological type was adenocarcinoma; patients of≤50 years of age group presented with well differentiated and moderately differentiated adenocarcinoma while those in >50 years age group with poorly differentiated growth. Most (82.66%) of the patients presented with advanced growth(T3/T4). Conclusion: 1) The incidence of gastric carcinoma in patients younger than 50 years was more common than Western world. 2) Patients are presenting more with lesion in distal stomach than Western world. 3) Gastric outlet obstruction and metastatic disease are commoner than abdominal lump and upper GI bleeding. The latter being the commoner presentations in Western world. 4) Regarding the histological type, adenocarcinoma are commoner than in Western world and 5) Patients with signet cell subtype are much less than Western world.http://ajms.alameenmedical.org/ArticlePDFs%5CAJMS%20V5.N4.2012%20p%20398-402.pdfstomachdemographycarcinomapathology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Shyamal Kumar Halder Prosanta Kumar Bhattacharjee Partha Bhar Prasenjit Bhattacharya Anadi Pachaury Ranu Roy Biswas Pranjal Pandey |
spellingShingle |
Shyamal Kumar Halder Prosanta Kumar Bhattacharjee Partha Bhar Prasenjit Bhattacharya Anadi Pachaury Ranu Roy Biswas Pranjal Pandey Demographic and clinico-pathological profile of carcinoma stomach in a tertiary referral centre of Eastern India Al Ameen Journal of Medical Sciences stomach demography carcinoma pathology |
author_facet |
Shyamal Kumar Halder Prosanta Kumar Bhattacharjee Partha Bhar Prasenjit Bhattacharya Anadi Pachaury Ranu Roy Biswas Pranjal Pandey |
author_sort |
Shyamal Kumar Halder |
title |
Demographic and clinico-pathological profile of carcinoma stomach in a tertiary referral centre of Eastern India |
title_short |
Demographic and clinico-pathological profile of carcinoma stomach in a tertiary referral centre of Eastern India |
title_full |
Demographic and clinico-pathological profile of carcinoma stomach in a tertiary referral centre of Eastern India |
title_fullStr |
Demographic and clinico-pathological profile of carcinoma stomach in a tertiary referral centre of Eastern India |
title_full_unstemmed |
Demographic and clinico-pathological profile of carcinoma stomach in a tertiary referral centre of Eastern India |
title_sort |
demographic and clinico-pathological profile of carcinoma stomach in a tertiary referral centre of eastern india |
publisher |
Al Ameen Medical College |
series |
Al Ameen Journal of Medical Sciences |
issn |
0974-1143 |
publishDate |
2012-10-01 |
description |
Objectives: This prospective study was done to assess the incidence, clinical presentations, histopathological subtypes of gastric adenocarcinoma in a referral institute of Eastern India. Methods: The patients admitted with diagnosis of gastric carcinoma in a tertiary referral hospital in Eastern India between January2006 to December2010 were included in this study. Data were compiled and analyzed with regards to their age, sex, socioeconomic status, their clinical presentations, site of lesion & histopathological subtypes. Results: 150 patients were included in this study of which 50 patients were of ≤50 years age. The median age group was 57 years. The male: female ratio was 2.3:1. Most of the patients were from lower socioeconomic strata (55.33%). Anemia (41.33%) and weight loss (38%) were the predominant presenting features irrespective of age, whereas gastric outlet obstruction due to antral growths was the commonest presentation in patients of ≤50 years age group. The most common histopathological type was adenocarcinoma; patients of≤50 years of age group presented with well differentiated and moderately differentiated adenocarcinoma while those in >50 years age group with poorly differentiated growth. Most (82.66%) of the patients presented with advanced growth(T3/T4). Conclusion: 1) The incidence of gastric carcinoma in patients younger than 50 years was more common than Western world. 2) Patients are presenting more with lesion in distal stomach than Western world. 3) Gastric outlet obstruction and metastatic disease are commoner than abdominal lump and upper GI bleeding. The latter being the commoner presentations in Western world. 4) Regarding the histological type, adenocarcinoma are commoner than in Western world and 5) Patients with signet cell subtype are much less than Western world. |
topic |
stomach demography carcinoma pathology |
url |
http://ajms.alameenmedical.org/ArticlePDFs%5CAJMS%20V5.N4.2012%20p%20398-402.pdf |
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