Surface phenotype and functionality of WNV specific T cells differ with age and disease severity.
West Nile virus (WNV) infection can result in severe neuroinvasive disease, particularly in persons with advanced age. As rodent models demonstrate that T cells play an important role in limiting WNV infection, and strong T cell responses to WNV have been observed in humans, we postulated that inade...
Main Authors: | Paolo Piazza, Curtis P McMurtrey, Alina Lelic, Robert L Cook, Rachel Hess, Eric Yablonsky, Luann Borowski, Mark B Loeb, Jonathan L Bramson, William H Hildebrand, Charles R Rinaldo |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-12-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3001480?pdf=render |
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