Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series

• Main Authors: Taddio Andrea, Cimaz Rolando, Caputo Roberto, de Libero Cinzia, Di Grande Laura, Simonini Gabriele, Mori Francesca, Novembre Elio, Pucci Neri
• Format: Article
• Language: English
• Published: BMC 2011-11-01
• Series: Pediatric Rheumatology Online Journal
• Subjects: Vernal keratoconjunctivitis; Anterior uveitis; treatment; Tacrolimus; children
• Online Access: http://www.ped-rheum.com/content/9/1/34

<p>Abstract</p> <p>Uveitis treatment involves topical corticosteroids along with cycloplegic-mydriatics. Particularly severe cases may require systemic corticosteroids and immunosuppressive drugs. Vernal keratoconjunctivitis (VKC) treatment consists of a brief period of topical corticosteroids and/or cyclosporine. In patients refractory to traditional treatment, the use of 0.1% topical ophtalmic FK- 506 (tacrolimus) ointment has been occasionally reported.</p> <p>This is the first report of the coexistence of uveitis and VKC. The documented response to topical tacrolimus eyedrop of uveitis and VKC is also of interest, in particular since to our knowledge there are no published reports on its clinical use in uveitis.</p>