Generation of pancreatic β cells for treatment of diabetes: advances and challenges

Generation of pancreatic β cells for treatment of diabetes: advances and challenges

Abstract Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are considered attractive sources of pancreatic β cells and islet organoids. Recently, several reports presented that hESC/iPSC-derived cells enriched with specific transcription factors can form glucose-responsive...

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Bibliographic Details
Main Authors: Hussain Md. Shahjalal, Ahmed Abdal Dayem, Kyung Min Lim, Tak-il Jeon, Ssang-Goo Cho
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Stem Cell Research & Therapy
Subjects:
Embryonic stem cells (ESC)
Induced pluripotent stem cells (iPSC)
Differentiation
Pancreatic β cell
Islet organoids
Transplantation
Online Access:http://link.springer.com/article/10.1186/s13287-018-1099-3

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