IMMUNOLOGICAL PARAMETERS, FUNCTIONAL AND METABOLIC ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH BASAL CELL SKIN CARCINOMA

IMMUNOLOGICAL PARAMETERS, FUNCTIONAL AND METABOLIC ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH BASAL CELL SKIN CARCINOMA

Abstract. Twenty patients with basal cell skin carcinoma at the age of 56 to 70 years have been included into study. We have investigated multiple parameters of cellular and humoral immunity, features of phagocytic activity, spontaneous and stimulated chemiluminescence of peripheral blood neutrophil...

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Main Authors: L. M. Kurtasova, G. A. Arutyunyan, E. A. Shkapova, A. E. Pobilat
Format: Article
Language:Russian
Published: SPb RAACI 2014-07-01
Series:Medicinskaâ Immunologiâ
Subjects:
immunity
phagocytosis
chemiluminescence
basal cell skin cancer
Online Access:https://www.mimmun.ru/mimmun/article/view/640
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spelling doaj-a469041c04ad40508527121109294e6b2021-07-29T09:02:28ZrusSPb RAACIMedicinskaâ Immunologiâ1563-06252313-741X2014-07-0114656156510.15789/1563-0625-2012-6-561-565637IMMUNOLOGICAL PARAMETERS, FUNCTIONAL AND METABOLIC ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH BASAL CELL SKIN CARCINOMAL. M. Kurtasova0G. A. Arutyunyan1E. A. Shkapova2A. E. Pobilat3Красноярский государственный медицинский университет имени проф. В.Ф. Войно-Ясенецкого, г. КрасноярскКрасноярский краевой клинический онкологический диспансер имени А.И. Крыжановского, г. КрасноярскКрасноярский краевой клинический онкологический диспансер имени А.И. Крыжановского, г. КрасноярскКрасноярский государственный медицинский университет имени проф. В.Ф. Войно-Ясенецкого, г. КрасноярскAbstract. Twenty patients with basal cell skin carcinoma at the age of 56 to 70 years have been included into study. We have investigated multiple parameters of cellular and humoral immunity, features of phagocytic activity, spontaneous and stimulated chemiluminescence of peripheral blood neutrophils. Distinct changes in blood lymphocyte subsets have been assessed by immunophenotyping. Changes in serum immunoglobulin profiles and increased levels of circulating immune complexes were revealed. Altered phagocytic activity and oxygen-dependent metabolism of blood neutrophils were also detected.https://www.mimmun.ru/mimmun/article/view/640immunityphagocytosischemiluminescencebasal cell skin cancer
collection DOAJ
language Russian
format Article
sources DOAJ
author L. M. Kurtasova
G. A. Arutyunyan
E. A. Shkapova
A. E. Pobilat
spellingShingle L. M. Kurtasova
G. A. Arutyunyan
E. A. Shkapova
A. E. Pobilat
IMMUNOLOGICAL PARAMETERS, FUNCTIONAL AND METABOLIC ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH BASAL CELL SKIN CARCINOMA
Medicinskaâ Immunologiâ
immunity
phagocytosis
chemiluminescence
basal cell skin cancer
author_facet L. M. Kurtasova
G. A. Arutyunyan
E. A. Shkapova
A. E. Pobilat
author_sort L. M. Kurtasova
title IMMUNOLOGICAL PARAMETERS, FUNCTIONAL AND METABOLIC ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH BASAL CELL SKIN CARCINOMA
title_short IMMUNOLOGICAL PARAMETERS, FUNCTIONAL AND METABOLIC ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH BASAL CELL SKIN CARCINOMA
title_full IMMUNOLOGICAL PARAMETERS, FUNCTIONAL AND METABOLIC ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH BASAL CELL SKIN CARCINOMA
title_fullStr IMMUNOLOGICAL PARAMETERS, FUNCTIONAL AND METABOLIC ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH BASAL CELL SKIN CARCINOMA
title_full_unstemmed IMMUNOLOGICAL PARAMETERS, FUNCTIONAL AND METABOLIC ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH BASAL CELL SKIN CARCINOMA
title_sort immunological parameters, functional and metabolic activity of blood neutrophils in patients with basal cell skin carcinoma
publisher SPb RAACI
series Medicinskaâ Immunologiâ
issn 1563-0625
2313-741X
publishDate 2014-07-01
description Abstract. Twenty patients with basal cell skin carcinoma at the age of 56 to 70 years have been included into study. We have investigated multiple parameters of cellular and humoral immunity, features of phagocytic activity, spontaneous and stimulated chemiluminescence of peripheral blood neutrophils. Distinct changes in blood lymphocyte subsets have been assessed by immunophenotyping. Changes in serum immunoglobulin profiles and increased levels of circulating immune complexes were revealed. Altered phagocytic activity and oxygen-dependent metabolism of blood neutrophils were also detected.
topic immunity
phagocytosis
chemiluminescence
basal cell skin cancer
url https://www.mimmun.ru/mimmun/article/view/640
work_keys_str_mv AT lmkurtasova immunologicalparametersfunctionalandmetabolicactivityofbloodneutrophilsinpatientswithbasalcellskincarcinoma
AT gaarutyunyan immunologicalparametersfunctionalandmetabolicactivityofbloodneutrophilsinpatientswithbasalcellskincarcinoma
AT eashkapova immunologicalparametersfunctionalandmetabolicactivityofbloodneutrophilsinpatientswithbasalcellskincarcinoma
AT aepobilat immunologicalparametersfunctionalandmetabolicactivityofbloodneutrophilsinpatientswithbasalcellskincarcinoma
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