Antibacterial activity of silver bionanocomposites synthesized by chemical reduction route

<p>Abstract</p> <p>Background</p> <p>The aim of this study is to investigate the functions of polymers and size of nanoparticles on the antibacterial activity of silver bionanocomposites (Ag BNCs). In this research, silver nanoparticles (Ag NPs) were incorporated into b...

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Main Authors: Bin Ahmad Mansor, Lim Jenn, Shameli Kamyar, Ibrahim Nor, Tay Mei Yen, Chieng Buong
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Chemistry Central Journal
Online Access:http://journal.chemistrycentral.com/content/6/1/101
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spelling doaj-a46ac657c47e42fd8b3cd119fbc461ae2021-08-02T20:34:06ZengBMCChemistry Central Journal1752-153X2012-09-016110110.1186/1752-153X-6-101Antibacterial activity of silver bionanocomposites synthesized by chemical reduction routeBin Ahmad MansorLim JennShameli KamyarIbrahim NorTay Mei YenChieng Buong<p>Abstract</p> <p>Background</p> <p>The aim of this study is to investigate the functions of polymers and size of nanoparticles on the antibacterial activity of silver bionanocomposites (Ag BNCs). In this research, silver nanoparticles (Ag NPs) were incorporated into biodegradable polymers that are chitosan, gelatin and both polymers via chemical reduction method in solvent in order to produce Ag BNCs. Silver nitrate and sodium borohydride were employed as a metal precursor and reducing agent respectively. On the other hand, chitosan and gelatin were added as a polymeric matrix and stabilizer. The antibacterial activity of different sizes of silver nanoparticles was investigated against Gram-positive and Gram-negative bacteria by the disk diffusion method using Mueller-Hinton Agar.</p> <p>Results</p> <p>The properties of Ag BNCs were studied as a function of the polymer weight ratio in relation to the use of chitosan and gelatin. The morphology of the Ag BNCs films and the distribution of the Ag NPs were also characterized. The diameters of the Ag NPs were measured and their size is less than 20 nm. The antibacterial trait of silver/chitosan/gelatin bionanocomposites was investigated. The silver ions released from the Ag BNCs and their antibacterial activities were scrutinized. The antibacterial activities of the Ag BNC films were examined against Gram-negative bacteria (<it>E. coli</it> and <it>P. aeruginosa</it>) and Gram-positive (<it>S. aureus</it> and <it>M. luteus</it>) by diffusion method using Muller-Hinton agar.</p> <p>Conclusions</p> <p>The antibacterial activity of Ag NPs with size less than 20 nm was demonstrated and showed positive results against Gram-negative and Gram-positive bacteria. The Ag NPs stabilized well in the polymers matrix.</p> http://journal.chemistrycentral.com/content/6/1/101
collection DOAJ
language English
format Article
sources DOAJ
author Bin Ahmad Mansor
Lim Jenn
Shameli Kamyar
Ibrahim Nor
Tay Mei Yen
Chieng Buong
spellingShingle Bin Ahmad Mansor
Lim Jenn
Shameli Kamyar
Ibrahim Nor
Tay Mei Yen
Chieng Buong
Antibacterial activity of silver bionanocomposites synthesized by chemical reduction route
Chemistry Central Journal
author_facet Bin Ahmad Mansor
Lim Jenn
Shameli Kamyar
Ibrahim Nor
Tay Mei Yen
Chieng Buong
author_sort Bin Ahmad Mansor
title Antibacterial activity of silver bionanocomposites synthesized by chemical reduction route
title_short Antibacterial activity of silver bionanocomposites synthesized by chemical reduction route
title_full Antibacterial activity of silver bionanocomposites synthesized by chemical reduction route
title_fullStr Antibacterial activity of silver bionanocomposites synthesized by chemical reduction route
title_full_unstemmed Antibacterial activity of silver bionanocomposites synthesized by chemical reduction route
title_sort antibacterial activity of silver bionanocomposites synthesized by chemical reduction route
publisher BMC
series Chemistry Central Journal
issn 1752-153X
publishDate 2012-09-01
description <p>Abstract</p> <p>Background</p> <p>The aim of this study is to investigate the functions of polymers and size of nanoparticles on the antibacterial activity of silver bionanocomposites (Ag BNCs). In this research, silver nanoparticles (Ag NPs) were incorporated into biodegradable polymers that are chitosan, gelatin and both polymers via chemical reduction method in solvent in order to produce Ag BNCs. Silver nitrate and sodium borohydride were employed as a metal precursor and reducing agent respectively. On the other hand, chitosan and gelatin were added as a polymeric matrix and stabilizer. The antibacterial activity of different sizes of silver nanoparticles was investigated against Gram-positive and Gram-negative bacteria by the disk diffusion method using Mueller-Hinton Agar.</p> <p>Results</p> <p>The properties of Ag BNCs were studied as a function of the polymer weight ratio in relation to the use of chitosan and gelatin. The morphology of the Ag BNCs films and the distribution of the Ag NPs were also characterized. The diameters of the Ag NPs were measured and their size is less than 20 nm. The antibacterial trait of silver/chitosan/gelatin bionanocomposites was investigated. The silver ions released from the Ag BNCs and their antibacterial activities were scrutinized. The antibacterial activities of the Ag BNC films were examined against Gram-negative bacteria (<it>E. coli</it> and <it>P. aeruginosa</it>) and Gram-positive (<it>S. aureus</it> and <it>M. luteus</it>) by diffusion method using Muller-Hinton agar.</p> <p>Conclusions</p> <p>The antibacterial activity of Ag NPs with size less than 20 nm was demonstrated and showed positive results against Gram-negative and Gram-positive bacteria. The Ag NPs stabilized well in the polymers matrix.</p>
url http://journal.chemistrycentral.com/content/6/1/101
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AT limjenn antibacterialactivityofsilverbionanocompositessynthesizedbychemicalreductionroute
AT shamelikamyar antibacterialactivityofsilverbionanocompositessynthesizedbychemicalreductionroute
AT ibrahimnor antibacterialactivityofsilverbionanocompositessynthesizedbychemicalreductionroute
AT taymeiyen antibacterialactivityofsilverbionanocompositessynthesizedbychemicalreductionroute
AT chiengbuong antibacterialactivityofsilverbionanocompositessynthesizedbychemicalreductionroute
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