A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization
Selective functionalization of aromatic compounds is important in synthetic chemistry. Here the authors report anN-heterocyclic carbene-catalysed approach for enantioselectively converting ortho-hydroxyaldehydes to cyclic products, via activation of both phenol and aldehyde groups.
Bibliographic Details
| Main Authors: |
Xingkuan Chen,
Hongling Wang,
Kazuki Doitomi,
Chong Yih Ooi,
Pengcheng Zheng,
Wangsheng Liu,
Hao Guo,
Song Yang,
Bao-An Song,
Hajime Hirao,
Yonggui Robin Chi |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2017-05-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms15598
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