Spatial Distribution of (R)-salbutamol in Rat Brain Following Nasal and Intravenous Administration Using DESI-MS

Spatial Distribution of (R)-salbutamol in Rat Brain Following Nasal and Intravenous Administration Using DESI-MS

Recent studies have shown that β2-Adrenoreceptor is a regulator of the a-synuclein gene driving risk of Parkinson’s disease. The β2-AR agonist (R)-salbutamol, eutomer of rac-salbutamol, may hold therapeutic potential for Parkinson’s disease (PD) following nasal...

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Bibliographic Details
Main Authors: Rui Zhang, Jie Wu, Siyu Liu, LiangJun Deng, Junhua Hu, Xi Chen, Wen Tan
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Pharmaceutics
Subjects:
parkinson’s disease
β2-adrenergic receptor
salbutamol
nasal administration
desorption electrospray ionization
Online Access:https://www.mdpi.com/1999-4923/12/1/35

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https://www.mdpi.com/1999-4923/12/1/35

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