A Rare Case of Esophageal Adenocarcinoma with Urinary Bladder Metastasis
Metastatic esophageal adenocarcinoma to the urinary bladder is extremely rare. We describe a previously healthy 49-year-old female with recent diagnosis of adenocarcinoma of the gastroesophageal junction with metastatic disease to the liver. Biopsy was positive for human epidermal growth factor rece...
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Online Access: | http://dx.doi.org/10.1155/2017/9343896 |
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doaj-a490bdd625f94208a6b67aa744a836a22020-11-25T00:44:59ZengHindawi LimitedCase Reports in Gastrointestinal Medicine2090-65282090-65362017-01-01201710.1155/2017/93438969343896A Rare Case of Esophageal Adenocarcinoma with Urinary Bladder MetastasisHeather Katz0Rahoma E. Saad1Krista Denning2Toni O. Pacioles3Department of Hematology/Oncology, Joan C. Edwards School of Medicine, Marshall University, 1600 Medical Center Dr, Huntington, WV 25701, USADepartment of Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, 1600 Medical Center Dr, Huntington, WV 25701, USADepartment of Pathology, Joan C. Edwards School of Medicine, Marshall University, 1600 Medical Center Dr, Huntington, WV 25701, USADepartment of Hematology/Oncology, Joan C. Edwards School of Medicine, Marshall University, 1600 Medical Center Dr, Huntington, WV 25701, USAMetastatic esophageal adenocarcinoma to the urinary bladder is extremely rare. We describe a previously healthy 49-year-old female with recent diagnosis of adenocarcinoma of the gastroesophageal junction with metastatic disease to the liver. Biopsy was positive for human epidermal growth factor receptor 2 (HER2) by Fluorescence In Situ Hybridization (FISH). She received six cycles of Cisplatin, 5-Fluorouracil, and Herceptin and subsequently developed symptomatic anemia and hematuria. Cystoscopy with retroflexion was performed and she received a transurethral resection of bladder tumor with fulguration. Pathology of the bladder tumor revealed similar morphology to her liver metastasis and immunohistochemical stains were consistent with metastatic esophageal cancer. Three weeks after being diagnosed with metachronous urinary bladder metastasis from esophageal adenocarcinoma primary, she expired. She only received her first cycle of palliative chemotherapy with Ramucirumab and Paclitaxel.http://dx.doi.org/10.1155/2017/9343896 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Heather Katz Rahoma E. Saad Krista Denning Toni O. Pacioles |
spellingShingle |
Heather Katz Rahoma E. Saad Krista Denning Toni O. Pacioles A Rare Case of Esophageal Adenocarcinoma with Urinary Bladder Metastasis Case Reports in Gastrointestinal Medicine |
author_facet |
Heather Katz Rahoma E. Saad Krista Denning Toni O. Pacioles |
author_sort |
Heather Katz |
title |
A Rare Case of Esophageal Adenocarcinoma with Urinary Bladder Metastasis |
title_short |
A Rare Case of Esophageal Adenocarcinoma with Urinary Bladder Metastasis |
title_full |
A Rare Case of Esophageal Adenocarcinoma with Urinary Bladder Metastasis |
title_fullStr |
A Rare Case of Esophageal Adenocarcinoma with Urinary Bladder Metastasis |
title_full_unstemmed |
A Rare Case of Esophageal Adenocarcinoma with Urinary Bladder Metastasis |
title_sort |
rare case of esophageal adenocarcinoma with urinary bladder metastasis |
publisher |
Hindawi Limited |
series |
Case Reports in Gastrointestinal Medicine |
issn |
2090-6528 2090-6536 |
publishDate |
2017-01-01 |
description |
Metastatic esophageal adenocarcinoma to the urinary bladder is extremely rare. We describe a previously healthy 49-year-old female with recent diagnosis of adenocarcinoma of the gastroesophageal junction with metastatic disease to the liver. Biopsy was positive for human epidermal growth factor receptor 2 (HER2) by Fluorescence In Situ Hybridization (FISH). She received six cycles of Cisplatin, 5-Fluorouracil, and Herceptin and subsequently developed symptomatic anemia and hematuria. Cystoscopy with retroflexion was performed and she received a transurethral resection of bladder tumor with fulguration. Pathology of the bladder tumor revealed similar morphology to her liver metastasis and immunohistochemical stains were consistent with metastatic esophageal cancer. Three weeks after being diagnosed with metachronous urinary bladder metastasis from esophageal adenocarcinoma primary, she expired. She only received her first cycle of palliative chemotherapy with Ramucirumab and Paclitaxel. |
url |
http://dx.doi.org/10.1155/2017/9343896 |
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