LOXL4 Abrogation Does Not Exaggerate Angiotensin II-Induced Thoracic or Abdominal Aortic Aneurysm in Mice

LOXL4 Abrogation Does Not Exaggerate Angiotensin II-Induced Thoracic or Abdominal Aortic Aneurysm in Mice

It has been shown that thoracic aortic aneurysm and dissection (TAAD) could be a Mendelian trait caused by a single gene mutation. The <i>LOX</i> gene mutation leads to the development of human TAAD. The <i>LOXL4</i> gene is a member of the lysyl oxidase gene family. We ident...

Full description

Bibliographic Details
Main Authors: Huimin Li, Jun Guo, Yiting Jia, Wei Kong, Wei Li
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Genes
Subjects:
angiotensin II
<i>LOXL4</i>
thoracic or abdominal aortic aneurysm
variants
whole-exome sequencing
Online Access:https://www.mdpi.com/2073-4425/12/4/513

Similar Items

Similar Items