Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease

Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease

The healthy oral microbiome is symbiotic with the human host, importantly providing colonization resistance against potential pathogens. Dental caries and periodontitis are two of the world’s most common and costly chronic infectious diseases and are caused by a localized dysbiosis of the oral micro...

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Bibliographic Details
Main Authors: Gajender Aleti, Jonathon L. Baker, Xiaoyu Tang, Ruth Alvarez, Márcia Dinis, Nini C. Tran, Alexey V. Melnik, Cuncong Zhong, Madeleine Ernst, Pieter C. Dorrestein, Anna Edlund
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mBio
Subjects:
biosynthetic gene clusters
caries
genome mining
oral microbiome
periodontitis
small molecules
Online Access:https://doi.org/10.1128/mBio.00321-19

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