Neuronal Correlates of Individual Differences in the Big Five Personality Traits: Evidences from Cortical Morphology and Functional Homogeneity
There have been many neuroimaging studies of human personality traits, and it have already provided glimpse into the neurobiology of complex traits. And most of previous studies adopt voxel-based morphology (VBM) analysis to explore the brain-personality mechanism from two levels (vertex and regiona...
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doaj-a4cab2f8c36d45308b9fb854e3f1a1522020-11-24T22:20:49ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2017-07-011110.3389/fnins.2017.00414269388Neuronal Correlates of Individual Differences in the Big Five Personality Traits: Evidences from Cortical Morphology and Functional HomogeneityTing Li0Xu Yan1Yuan Li2Junjie Wang3Qiang Li4Hong Li5Junfeng Li6Department of Radiology, Heping Hospital of Changzhi Medical CollegeShanxi, ChinaDepartment of Health Care, Changzhi Medical CollegeShanxi, ChinaDepartment of Radiology, Heping Hospital of Changzhi Medical CollegeShanxi, ChinaDepartment of Psychiatry, First Hospital of Shanxi Medical UniversityShanxi, ChinaDepartment of Radiology, Heping Hospital of Changzhi Medical CollegeShanxi, ChinaDepartment of Psychiatry, First Hospital of Shanxi Medical UniversityShanxi, ChinaDepartment of Radiology, Heping Hospital of Changzhi Medical CollegeShanxi, ChinaThere have been many neuroimaging studies of human personality traits, and it have already provided glimpse into the neurobiology of complex traits. And most of previous studies adopt voxel-based morphology (VBM) analysis to explore the brain-personality mechanism from two levels (vertex and regional based), the findings are mixed with great inconsistencies and the brain-personality relations are far from a full understanding. Here, we used a new method of surface-based morphology (SBM) analysis, which provides better alignment of cortical landmarks to generate about the associations between cortical morphology and the personality traits across 120 healthy individuals at both vertex and regional levels. While to further reveal local functional correlates of the morphology-personality relationships, we related surface-based functional homogeneity measures to the regions identified in the regional-based SBM correlation. Vertex-wise analysis revealed that people with high agreeableness exhibited larger areas in the left superior temporal gyrus. Based on regional parcellation we found that extroversion was negatively related with the volume of the left lateral occipito-temporal gyrus and agreeableness was negatively associated with the sulcus depth of the left superior parietal lobule. Moreover, increased regional homogeneity in the left lateral occipito-temporal gyrus is related to the scores of extroversion, and increased regional homogeneity in the left superior parietal lobule is related to the scores of agreeableness. These findings provide supporting evidence of a link between personality and brain structural mysteries with a method of SBM, and further suggest that local functional homogeneity of personality traits has neurobiological relevance that is likely based on anatomical substrates.http://journal.frontiersin.org/article/10.3389/fnins.2017.00414/fullpersonality traitsresting-state fMRIcortical morphologyregional homogeneitygeneral linear model |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ting Li Xu Yan Yuan Li Junjie Wang Qiang Li Hong Li Junfeng Li |
spellingShingle |
Ting Li Xu Yan Yuan Li Junjie Wang Qiang Li Hong Li Junfeng Li Neuronal Correlates of Individual Differences in the Big Five Personality Traits: Evidences from Cortical Morphology and Functional Homogeneity Frontiers in Neuroscience personality traits resting-state fMRI cortical morphology regional homogeneity general linear model |
author_facet |
Ting Li Xu Yan Yuan Li Junjie Wang Qiang Li Hong Li Junfeng Li |
author_sort |
Ting Li |
title |
Neuronal Correlates of Individual Differences in the Big Five Personality Traits: Evidences from Cortical Morphology and Functional Homogeneity |
title_short |
Neuronal Correlates of Individual Differences in the Big Five Personality Traits: Evidences from Cortical Morphology and Functional Homogeneity |
title_full |
Neuronal Correlates of Individual Differences in the Big Five Personality Traits: Evidences from Cortical Morphology and Functional Homogeneity |
title_fullStr |
Neuronal Correlates of Individual Differences in the Big Five Personality Traits: Evidences from Cortical Morphology and Functional Homogeneity |
title_full_unstemmed |
Neuronal Correlates of Individual Differences in the Big Five Personality Traits: Evidences from Cortical Morphology and Functional Homogeneity |
title_sort |
neuronal correlates of individual differences in the big five personality traits: evidences from cortical morphology and functional homogeneity |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Neuroscience |
issn |
1662-453X |
publishDate |
2017-07-01 |
description |
There have been many neuroimaging studies of human personality traits, and it have already provided glimpse into the neurobiology of complex traits. And most of previous studies adopt voxel-based morphology (VBM) analysis to explore the brain-personality mechanism from two levels (vertex and regional based), the findings are mixed with great inconsistencies and the brain-personality relations are far from a full understanding. Here, we used a new method of surface-based morphology (SBM) analysis, which provides better alignment of cortical landmarks to generate about the associations between cortical morphology and the personality traits across 120 healthy individuals at both vertex and regional levels. While to further reveal local functional correlates of the morphology-personality relationships, we related surface-based functional homogeneity measures to the regions identified in the regional-based SBM correlation. Vertex-wise analysis revealed that people with high agreeableness exhibited larger areas in the left superior temporal gyrus. Based on regional parcellation we found that extroversion was negatively related with the volume of the left lateral occipito-temporal gyrus and agreeableness was negatively associated with the sulcus depth of the left superior parietal lobule. Moreover, increased regional homogeneity in the left lateral occipito-temporal gyrus is related to the scores of extroversion, and increased regional homogeneity in the left superior parietal lobule is related to the scores of agreeableness. These findings provide supporting evidence of a link between personality and brain structural mysteries with a method of SBM, and further suggest that local functional homogeneity of personality traits has neurobiological relevance that is likely based on anatomical substrates. |
topic |
personality traits resting-state fMRI cortical morphology regional homogeneity general linear model |
url |
http://journal.frontiersin.org/article/10.3389/fnins.2017.00414/full |
work_keys_str_mv |
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