Clinical Outcomes of Heart-Lung Transplantation: Review of 10 Single-Center Consecutive Patients
Background: Heart-lung transplantation (HLT) has provided hope to patients with end-stage lung disease and irreversible heart dysfunction. We reviewed the clinical outcomes of 10 patients who underwent heart-lung transplantation at Asan Medical Center. Methods: Between July 2010 and August 2014, a...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Korean Society for Thoracic and Cardiovascular Surgery
2016-06-01
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Series: | Korean Journal of Thoracic and Cardiovascular Surgery |
Subjects: | |
Online Access: | http://www.kjtcvs.org/journal/download_pdf.php?doi=10.5090/kjtcs.2016.49.3.157 |
Summary: | Background: Heart-lung transplantation (HLT) has provided hope to patients with end-stage lung disease and irreversible
heart dysfunction. We reviewed the clinical outcomes of 10 patients who underwent heart-lung transplantation
at Asan Medical Center. Methods: Between July 2010 and August 2014, a total of 11 patients underwent
HLT at Asan Medical Center. After excluding one patient who underwent concomitant liver transplantation, 10
patients were enrolled in our study. We reviewed the demographics of the donors and the recipients’ baseline information,
survival rate, cause of death, and postoperative complications. All patients underwent follow-up, with a
mean duration of 26.1±16.7 months. Results: Early death occurred in two patients (20%) due to septic shock.
Late death occurred in three patients (38%) due to bronchiolitis obliterans (n=2) and septic shock (n=1), although
these patients survived for 22, 28, and 42 months, respectively. The actuarial survival rates at one year, two
years, and three years after HLT were 80%, 67%, and 53%, respectively. Conclusion: HLT is a procedure that is
rarely performed in Korea, even in medical centers with large heart and lung transplant programs. In order to achieve
acceptable clinical outcomes, it is critical to carefully choose the donor and the recipient and to be certain
that all aspects of the transplant procedure are planned in advance with the greatest care. |
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ISSN: | 2233-601X 2093-6516 |