Bcl-xL Is Required by Primary Hippocampal Neurons during Development to Support Local Energy Metabolism at Neurites
B-cell lymphoma-extra large (Bcl-xL) is a mitochondrial protein known to inhibit mitochondria-dependent intrinsic apoptotic pathways. An increasing number of studies have demonstrated that Bcl-xL is critical in regulating neuronal energy metabolism and has a protective role in pathologies associated...
Main Authors: | Joseph Jansen, Madison Scott, Emma Amjad, Allison Stumpf, Kimberly H. Lackey, Kim A. Caldwell, Han-A Park |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-7737/10/8/772 |
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