Bcl-xL Is Required by Primary Hippocampal Neurons during Development to Support Local Energy Metabolism at Neurites

Bcl-xL Is Required by Primary Hippocampal Neurons during Development to Support Local Energy Metabolism at Neurites

B-cell lymphoma-extra large (Bcl-xL) is a mitochondrial protein known to inhibit mitochondria-dependent intrinsic apoptotic pathways. An increasing number of studies have demonstrated that Bcl-xL is critical in regulating neuronal energy metabolism and has a protective role in pathologies associated...

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Bibliographic Details
Main Authors: Joseph Jansen, Madison Scott, Emma Amjad, Allison Stumpf, Kimberly H. Lackey, Kim A. Caldwell, Han-A Park
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biology
Subjects:
Bcl-xL
mitochondria
motility
ATP
neurite
Online Access:https://www.mdpi.com/2079-7737/10/8/772

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