Is T2 mapping reliable in evaluation of native and repair cartilage tissue of the knee?
Abstract Purpose To evaluate the effect of imaging plane and experience of observers on the reliability of T2 mapping of native and repair cartilage tissue of the knee. Methods Fifteen consecutive patients from two randomised controlled trials (RCTs) were included in this cross-sectional study. Pati...
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doaj-a4d09f6b5a414706bd8e66981bf662f72021-05-02T11:44:14ZengSpringerOpenJournal of Experimental Orthopaedics2197-11532021-04-018111010.1186/s40634-021-00350-1Is T2 mapping reliable in evaluation of native and repair cartilage tissue of the knee?Hasan Banitalebi0Christian Owesen1Asbjørn Årøen2Hang Thi Tran3Tor Åge Myklebust4Per-Henrik Randsborg5Department of Diagnostic Imaging, Akershus University HospitalDepartment of Orthopaedic Surgery, Akershus University HospitalInstitute of Clinical Medicine, University of OsloDepartment of Diagnostic Imaging, Akershus University HospitalDepartment of Research and Innovation, Møre and Romsdal Hospital TrustDepartment of Orthopaedic Surgery, Akershus University HospitalAbstract Purpose To evaluate the effect of imaging plane and experience of observers on the reliability of T2 mapping of native and repair cartilage tissue of the knee. Methods Fifteen consecutive patients from two randomised controlled trials (RCTs) were included in this cross-sectional study. Patients with an isolated knee cartilage lesion were randomised to receive either debridement or microfracture (RCT 1) or debridement or autologous chondrocyte implantation (RCT 2). T2 mapping was performed in coronal and sagittal planes two years postoperatively. A musculoskeletal radiologist, a resident of radiology and two orthopaedic surgeons measured the T2 values independently. Intraclass Correlation Coefficient (ICC) with 95% Confidence Intervals was used to calculate the inter- and intraobserver agreement. Results Mean age for the patients was 36.8 ± 11 years, 8 (53%) were men. The overall interobserver agreement varied from poor to good with ICCs in the range of 0.27– 0.76 for native cartilage and 0.00 – 0.90 for repair tissue. The lowest agreement was achieved for evaluations of repair cartilage tissue. The estimated ICCs suggested higher inter- and intraobserver agreement for radiologists. On medial femoral condyles, T2 values were higher for native cartilage on coronal images (p < 0.001) and for repair tissue on sagittal images (p < 0.001). Conclusions The reliability of T2 mapping of articular cartilage is influenced by the imaging plane and the experience of the observers. This influence may be more profound for repair cartilage tissue. This is important to consider when using T2 mapping to measure outcomes after cartilage repair surgery. Trial registration ClinicalTrials.gov, NCT02637505 and NCT02636881 , registered December 2015. Level of evidence II, based on prospective data from two RCTs.https://doi.org/10.1186/s40634-021-00350-1T2 mappingMRIArticular cartilageReliabilityCartilage repairAutologous chondrocyte implantation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hasan Banitalebi Christian Owesen Asbjørn Årøen Hang Thi Tran Tor Åge Myklebust Per-Henrik Randsborg |
spellingShingle |
Hasan Banitalebi Christian Owesen Asbjørn Årøen Hang Thi Tran Tor Åge Myklebust Per-Henrik Randsborg Is T2 mapping reliable in evaluation of native and repair cartilage tissue of the knee? Journal of Experimental Orthopaedics T2 mapping MRI Articular cartilage Reliability Cartilage repair Autologous chondrocyte implantation |
author_facet |
Hasan Banitalebi Christian Owesen Asbjørn Årøen Hang Thi Tran Tor Åge Myklebust Per-Henrik Randsborg |
author_sort |
Hasan Banitalebi |
title |
Is T2 mapping reliable in evaluation of native and repair cartilage tissue of the knee? |
title_short |
Is T2 mapping reliable in evaluation of native and repair cartilage tissue of the knee? |
title_full |
Is T2 mapping reliable in evaluation of native and repair cartilage tissue of the knee? |
title_fullStr |
Is T2 mapping reliable in evaluation of native and repair cartilage tissue of the knee? |
title_full_unstemmed |
Is T2 mapping reliable in evaluation of native and repair cartilage tissue of the knee? |
title_sort |
is t2 mapping reliable in evaluation of native and repair cartilage tissue of the knee? |
publisher |
SpringerOpen |
series |
Journal of Experimental Orthopaedics |
issn |
2197-1153 |
publishDate |
2021-04-01 |
description |
Abstract Purpose To evaluate the effect of imaging plane and experience of observers on the reliability of T2 mapping of native and repair cartilage tissue of the knee. Methods Fifteen consecutive patients from two randomised controlled trials (RCTs) were included in this cross-sectional study. Patients with an isolated knee cartilage lesion were randomised to receive either debridement or microfracture (RCT 1) or debridement or autologous chondrocyte implantation (RCT 2). T2 mapping was performed in coronal and sagittal planes two years postoperatively. A musculoskeletal radiologist, a resident of radiology and two orthopaedic surgeons measured the T2 values independently. Intraclass Correlation Coefficient (ICC) with 95% Confidence Intervals was used to calculate the inter- and intraobserver agreement. Results Mean age for the patients was 36.8 ± 11 years, 8 (53%) were men. The overall interobserver agreement varied from poor to good with ICCs in the range of 0.27– 0.76 for native cartilage and 0.00 – 0.90 for repair tissue. The lowest agreement was achieved for evaluations of repair cartilage tissue. The estimated ICCs suggested higher inter- and intraobserver agreement for radiologists. On medial femoral condyles, T2 values were higher for native cartilage on coronal images (p < 0.001) and for repair tissue on sagittal images (p < 0.001). Conclusions The reliability of T2 mapping of articular cartilage is influenced by the imaging plane and the experience of the observers. This influence may be more profound for repair cartilage tissue. This is important to consider when using T2 mapping to measure outcomes after cartilage repair surgery. Trial registration ClinicalTrials.gov, NCT02637505 and NCT02636881 , registered December 2015. Level of evidence II, based on prospective data from two RCTs. |
topic |
T2 mapping MRI Articular cartilage Reliability Cartilage repair Autologous chondrocyte implantation |
url |
https://doi.org/10.1186/s40634-021-00350-1 |
work_keys_str_mv |
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