Сandidate SNP-markers of rheumatoid arthritis that can significantly alter the affinity of the TATA-binding protein for human gene promoters
Rheumatoid polyarthritis (RA) is an autoimmune disease with autoantibodies, including antibodies to citrullant antigens and proinflammatory cytokines, such as TNF-α and IL-6, which are involved in the induction of chronic synovitis, bone erosion, followed by deformity. Immunopathogenesis is based on...
Main Authors: | I. V. Chadaeva, D. A. Rasskazov, E. B. Sharypova, I. A. Drachkova, E. A. Oshchepkova, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko, N. A. Kolchanov, V. A. Kozlov |
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Format: | Article |
Language: | English |
Published: |
Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences
2020-01-01
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Series: | Vavilovskij Žurnal Genetiki i Selekcii |
Subjects: | |
Online Access: | https://vavilov.elpub.ru/jour/article/view/2398 |
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