Enhanced cancer metastasis in mice deficient in vasohibin-1 gene.

Enhanced cancer metastasis in mice deficient in vasohibin-1 gene.

Vasohibin-1 (VASH1) is isolated as an endogenous angiogenesis inhibitor produced by the vascular endothelium. We previously reported that tumor growth and tumor angiogenesis were augmented in VASH1 (-/-) mice. Here we examined whether VASH1 plays any role in cancer metastasis. When Lewis lung carcin...

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Bibliographic Details
Main Authors: Soichi Ito, Hiroki Miyashita, Yasuhiro Suzuki, Miho Kobayashi, Susumu Satomi, Yasufumi Sato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3774736?pdf=render

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